Tetanus Clinical Trial
Official title:
Safety and Immunogenicity of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (ADACEL®) in Persons ≥65 Years of Age
It is well recognized that older adults can contract pertussis, suffer its complications,
and unwittingly transmit it to close contacts, which may well include infants too young to
have received their primary series of DTaP vaccinations. ADACEL® vaccine is currently
licensed in the US for persons 11 - 64 years of age, but no pertussis vaccine is yet
approved for administration to older adults. The most widely used Td vaccine in the US,
DECAVAC®, has no upper limit on its age indication.
The purpose of this trial is to describe the safety and immunogenicity of ADACEL® vaccine
among individuals ≥ 65 years of age.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
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