Hypogonadism Clinical Trial
Official title:
Development and Validation of in Vitro Cell-based Bioassays for Nuclear Receptor Activation by Human Serum
This is a prospective biobank set up to collect serum from patients with disorders associated with changes in androgens, estrogens or sex hormone-binding globulin (SHBG), before and/or after treatment.
In vitro cell-based bioassays may be a technique to measure serum androgen or estrogen
bioactivity. In this study investigators are collecting serum (and if possible, urine)
samples from different cohorts of patients, before and/or after treatment.
The aim is to measure androgens, estrogens and SHBG as well as in vitro bioactivity with
newly developed cell-based bioassays, and to compare different techniques to each other as
well as to clinical endpoints available in the patient's Electronic Health Record.
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