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Term Infant clinical trials

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NCT ID: NCT05209269 Completed - Work of Breathing Clinical Trials

Work of Breathing in Term Infants

Start date: April 22, 2022
Phase:
Study type: Observational

This is a prospective observational cohort study conducted in the mother-baby unit at ChristianaCare. The study is designed to assess work of breathing indices and oxygen saturation stability at discharge in full-term infants. Data obtained will be used to perform a comparative analysis on work of breathing data for premature infants obtained from our previous study. We hypothesize full term (≥37 weeks gestation) infants have decreased work of breathing indices (i.e., phase angle) compared to premature infants (born 26-37 weeks gestation) at discharge.

NCT ID: NCT04089540 Completed - Preterm Infant Clinical Trials

New Intubation Method to Achieve Circulatory Stability and to Reduce Number of Intubation Attempts in Neonates

NOONA
Start date: October 2016
Phase: N/A
Study type: Interventional

This is a randomized controlled pilot study investigating a new intubation method in newborn infants. In contrast to the conventional intubation method, in the new method the respirator is connected to the tube prior to insertion into the mouth (oral intubation) or into the nose (nasopharyngeal intubation). As a result, an oxygen flow is already administered via the tube during the intubation process. Heart rate, arterial oxygen saturation (SpO2) and cerebral tissue oxygenation (using near-infrared spectroscopy) are recorded in both the study and control groups during intubation. Hypothesis - The new intubation method is safe - The new intubation method leads to a reduction in the number of intubation attempts - The new intubation method leads to a reduction of desaturations and bradycardia during intubation - In the long term, it could lead to a reduction in morbidity and mortality

NCT ID: NCT03748914 Completed - Preterm Infant Clinical Trials

C-UCM and Cerebral Oxygenation and Perfusion

Start date: November 21, 2018
Phase: N/A
Study type: Interventional

In this randomized controlled Pilot study the effects of cut-umbilical cord milking on cerebral oxygenation and perfusion measured via near-infrared spectroscopy (NIRS) and the effects on stroke volume (SV) and cardiac output (CO) also measured non-invasively in term and preterm infants are evaluated for the first 15 minutes after birth and compared to a control group.