Embryo Culture at a Constant Temperature of 36.6°C or 37.1°C

Temperature; Extreme, Exposure Clinical Trial

Official title: Embryo Culture at a Constant Temperature of 36.6°C or 37.1°C: A Randomized Controlled Trial

Status Completed

Clinical Trial Summary

On the day of oocyte retrieval, participants will be randomized to stable culture at 37.1°C or 36.6°C with the ultimate aim of finding a difference in clincial pregnancies.

Clinical Trial Description

A previous study in our centre analysed stable embryo culture at 36.6°C and 37.1°C, on sibling oocytes. The primary aim was to analyse possible differneces in embryo development (utilization rate) up to day 5/6. In this study, the investigators found a high difference in clinical pregnancy rate between both groups (46.4% versus 77.4%). Since this study was not powered to find differences in clincial pregnancy rates between both groups, this RCT was especially powered as a superiority trial to find differences in clincial pregnancy rates between both groups. On the day of oocyte retrieval, patients will be allocated to culture at one of both temperatures. ;

Related Conditions & MeSH terms

• Temperature; Extreme, Exposure

• NCT number: NCT03548532
• Study type: Interventional
• Source: Universitair Ziekenhuis Brussel
• Status: Completed
• Phase: N/A
• Start date: November 1, 2017
• Completion date: January 18, 2023