PAI-1 Expression in Non-scarring Hair Loss

Status Terminated

Clinical Trial Summary

This study will investigate whether subjects who suffer from hair loss have increased levels of PAI-1 compared to age-matched control subjects. The level of PAI-1 expression will be determined in subjects without hair loss and in subjects with non-scarring hair loss, including androgenetic alopecia, telogen effluvium and alopecia areata.

Clinical Trial Description

This study will compare the levels of PAI-1 expression in subjects with different forms of non-scarring hair loss and in these subjects vs normal age-matched controls. Hair loss subjects will have their Northwestern Memorial Hospital and Northwestern Medical Faculty Foundation medical records reviewed to ensure they meet inclusion and exclusion criteria. All subjects will have a 4 mm punch biopsy on the scalp. Tissue PAI-1 levels from scalp skin biopsies will be determined by immunohistochemical staining. Samples will be kept for approximately 15 years, after which time unused samples will be destroyed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02548689
Study type	Observational
Source	Northwestern University
Contact
Status	Terminated
Phase
Start date	July 2015
Completion date	June 2021

View Details

See also
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