Vitiligo Clinical Trial
Official title:
Effectivness of Topical Tacrolimus 0.03% Monotherapy in Patients With Vitiligo: Arandomized Controlled Trial
The study will evaluate the effectiveness of Tacrolimus 0.03% ointment monotherapy in patients with vitiligo. Patients will be treated for 6 months and followed for 3 months after treatment. All types of vitiligo will be included.
Study approval: The study was submitted for approval by Scientific and Ethical Committee at
Faculty of Medicine, Sohag University. An informed written consent will be obtained from all
participants.
Study design: randomized controlled trial. Study population: the study will include patients
who attend the outpatient Clinic of Dermatology & Venereology and Andrology, Faculty of
Medicine, Sohag University in corporation with Farshot General Hospital. Women who are
pregnant or lactating, children aged 2 years or less and patients with acute or chronic
disease that might affect skin barrier function will be excluded.
Patients and methods:
Study participants will be randomly divided into two treatment groups: group A will receive
0.03% tacrolimus ointment and group B will receive hydrocortisone acetate 1% ointment twice
daily for 6 months.
Patients will be evaluated at baseline and monthly intervals for 6 months and at 3 months
after stopping treatment.
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