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Tachypnea clinical trials

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NCT ID: NCT03006354 Completed - Clinical trials for Transient Tachypnea of the Newborn

nHFOV Versus nCPAP in Transient Tachypnea of the Newborn

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

In this prospective, randomised clinical trial the investigators aim to assess if nasal high frequency oscillatory ventilation (nHFOV) could be used as the primary modality of respiratory support in late preterm and term infants with transient tachypnea of the newborn requiring non-invasive ventilation.

NCT ID: NCT02965365 Completed - Clinical trials for Transient Tachypnea of the Newborn

PATET Ratio to Rule Out Transient Tachypnea of the Newborn

PATET
Start date: January 2016
Phase: N/A
Study type: Observational

This study aims to find out whether diagnosis of Transient Tachypnea of the Newborn(TTN) can be predicted via evaluating pulmonary artery Doppler indices.

NCT ID: NCT02837341 Completed - Tachypnea Clinical Trials

Camera-based Measurement of Respiratory Rates

Start date: December 2015
Phase: N/A
Study type: Interventional

Respiratory rate as an important predictor for adverse events, but still a neglected vital sign. Precise and simple measurement of the respiratory rate in volunteers by a new electronic camera device in different settings.

NCT ID: NCT02813954 Completed - Clinical trials for Respiratory Distress Syndrome

The Predictive Value of Amniotic Fluid pH and Electrolytes on Neonatal Respiratory Disorders

Start date: August 2015
Phase:
Study type: Observational [Patient Registry]

Amniotic fluid (AF) is a complex structure with a changing content by gestational time. AF pH can be affected by both maternal and fetal conditions such as preterm ruptures of membranes, prematurity and fetal distress. While fetal urine is the major content of AF since 20th gestational week, fetal lung liquid (FLL) also acts as a minor content. Secretion of FLL depends on chloride transport and postnatal clearance of FLL is provided by active reabsorption of sodium (Na) ions. Down-regulation of epithelial Na channels (ENaCs) and an increase of pulmonary compliance accompany to pulmonary adaptation developing at the first hours of life. Lower genomic expression of Na channels in airways is shown to be associated to respiratory distress syndrome (RDS) in preterm. Although pH and electrolyte value of AF is thought to be relevant to fetal and maternal conditions such as gestational age, antenatal steroids and preterm birth, there is no study about this topic in the literature.

NCT ID: NCT02691559 Completed - Clinical trials for Respiratory Distress Syndrome

The Possible Effect Of Amniotic Fluid pH On Neonatal Morbidities In Maternal Inflammation/Infection Associated Pregnancies

Start date: August 2015
Phase: N/A
Study type: Interventional

Amniotic fluid (AF) pH can be affected by the maternal and/or fetal conditions such as PPROM, prematurity or fetal distress. It is known that fetal urine is the major content of AF since 20th gestational week. Besides fetal alveolar fluid (FAF), gastrointestinal tract, umbilical cord and fetal side of placenta are important sources for AF. Bombesin-like peptides, 8-hydroxydeoxyguanosine in fetal urine and leukotriene E(4), lecithin, sphingomyelin, lamellar body in FAF are molecules acting on fetal lung maturation. Varying levels of these molecules relevant to the stage of lung maturation may constitute an association to AF pHTo detect the possible effect of AF pH on neonatal respiratory morbidities 1 milliliters of AF is aspirated during C-section before incision of membranes. pH value of AFs were analyzed by the blood gas machine (Siemens RAPIDLab®1200 Systems) of NICU. Maternal and neonatal demographic features and clinical outcomes, incidences of morbidities such as respiratory distress syndrome (RDS), transient tachypnea of the newborn (TTN) are all recorded.

NCT ID: NCT02570828 Completed - Clinical trials for Thermal Imaging, Neonatal Pneumonia, Tachypnea

Thermal Imaging in Neonates: A Feasibility Study in Healthy Babies and Babies With Suspected TTN

Start date: October 2015
Phase: Phase 1
Study type: Interventional

This is a study to evaluate thermal imaging as a technology to monitor the normal clearing of amniotic fluid from healthy newborns and newborns suspected of having a condition called transient tachypnea of the newborn, or TTN. Thermal images are taken using an imaging device that attaches to an iPhone. This device, commercially known as FLIR ONE, creates a non-identifiable image based on the heat pattern of an object. In this case, the object is a child's chest and back. It does not emit any radiation like an x-ray does.

NCT ID: NCT02372461 Completed - Pneumonia Clinical Trials

Randomized Trial of Amoxicillin Versus Placebo for (Fast Breathing) Pneumonia

RETAPP
Start date: November 9, 2014
Phase: N/A
Study type: Interventional

The relative benefits and risks of antibiotic therapy in WHO defined fast breathing pneumonia in pre-school children in resource limited settings are controversial both at an individual and public health level. Most infections are viral or self-limiting and non-selective drug treatment has contributed to the global epidemic of antibiotic resistance. There is no high quality trial evidence in managing children with fast breathing in community settings and the WHO itself has called for evidence on which to update guidance. The investigators proposed non inferiority trial comparing standard antibiotic treatment with placebo in poor urban slum settings in South Asia to address this deficit.

NCT ID: NCT01858129 Recruiting - Clinical trials for Transient Tachypnea of the Newborn

Inhaled Corticosteroids for the Treatment of Transient Tachypnea of the Newborn

Start date: March 2012
Phase: Phase 2
Study type: Interventional

Transient Tachypnea of the Newborn (TTN) is a common respiratory disorder affecting late preterm and term babies caused by lung edema resulting from delayed absorption of fetal alveolar lung fluid. The investigators hypothesize that ENAC expression will be up-regulated as a result of administration of corticosteroids. This effect will lead to enhanced absorption of fetal lung fluid finally treating TTN. The aim of our study will be to evaluate whether inhaled corticosteroids reduce respiratory distress and morbidity in late preterm and term neonates presenting with TTN.

NCT ID: NCT01517958 Completed - Clinical trials for Respiratory Distress Syndrome

Lung Ultrasound to Diagnose Transient Tachypnea of the Newborn (TTN) Versus Respiratory Distress Syndrome (RDS) in Neonates

Start date: October 2011
Phase: N/A
Study type: Observational

The investigators hypothesize that ultrasonography of the newborn lung can be used as an effective diagnostic tool in neonates ≥ 28 weeks gestation with early symptoms of respiratory distress.

NCT ID: NCT01499238 Recruiting - Clinical trials for Transient Tachypnea of Newborn

Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn

Start date: December 2011
Phase: Phase 4
Study type: Interventional

The investigators aimed to compare the efficacy of nasal SIMV and nasal CPAP in patients with wet lung.