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Safety and Efficacy of THR-1442 Compared to Dapagliflozin as Add-on Therapy to Metformin in T2DM

T2DM Clinical Trial

Official title:
A Multicenter, Randomized, Double-Blind, Parallel, Active-Controlled Phase III Study on Metformin Combined With THR-1442 or Dapagliflozin in T2DM

Clinical Trial Summary

The purpose of this study is to investigate the effect of THR-1442 compared to Dapagliflozin as an add-on therapy to metformin in lowering hemoglobin A1c (HbA1c) levels in subjects with type 2 diabetes mellitus (T2DM).

Clinical Trial Description

Approximately 390 subjects with inadequately controlled T2DM on metformin were to be recruited from China. Subjects were randomly assigned to receive THR-1442 tablet, 20 mg, or Dapagliflozin tavlet,10 mg, in a ratio of 1:1 once daily for 24 weeks. Subjects were to continue taking metformin for the duration of the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05159882
Study type Interventional
Source Newsoara Biopharma Co., Ltd.
Contact Owen Zhang
Phone 8621-52998027
Email owen.zhang@newsoara.com
Status Recruiting
Phase Phase 3
Start date April 15, 2021
Completion date September 30, 2022
View Details
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