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T2DM (Type 2 Diabetes Mellitus) clinical trials

View clinical trials related to T2DM (Type 2 Diabetes Mellitus).

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NCT ID: NCT05376969 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin

ENHANCE-MEXT
Start date: May 25, 2021
Phase: Phase 3
Study type: Interventional

A Multi-center, Open-label, Extension study to Evaluate the long term Safety and Efficacy of DWP16001 add-on to metformin in Patients with type 2 diabetes mellitus inadequately controlled on metformin

NCT ID: NCT05376930 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Study to Evaluate the Long Term Safety and Efficacy of DWP16001 Compared to Placebo in the Treatment of T2DM.

Start date: September 16, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is evaluate the long term safety and efficacy of DWP16001 compared to placebo in the treatment of type 2 diabetes mellitus.

NCT ID: NCT05369078 Recruiting - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Safety, Tolerance and Pharmacokinetics of THR-1442 in Chinese Healthy Subjects

Start date: December 1, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study was to investigate Safety, tolerability and pharmacokinetics in Chinese healthy subjects.

NCT ID: NCT05279911 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion

Start date: March 3, 2021
Phase: N/A
Study type: Interventional

This study aimed therefore to evaluate bone density (BD) and OPG levels in the peri-implant crevicular fluid (PICF) in lased controlled type II Diabetes Mellitus (T2DM) patients versus non-lased T2DM patients. 40 T2DM patients were included in this study. Implants were randomly inserted in 20 non-lased T2DM patients (Control) and 20 lased T2DM patients (Intervention). BD and OPG levels in the PICF were assessed in both groups at the follow up points.

NCT ID: NCT05260021 Active, not recruiting - Clinical trials for Diabetes Mellitus, Type 2

A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both

SURPASS-PEDS
Start date: April 13, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to learn more about the safety and efficacy of tirzepatide compared to placebo in children or teenagers with type 2 diabetes taking metformin, or basal insulin, or both. The overall study will last about 60 weeks with up to 14 clinic visits and 6 phone visits. Clinic visits will include blood sample collection, physical exam and questionnaire.

NCT ID: NCT04970940 Completed - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

The Drug-drug Interaction Study of AJU-A51R1 and AJU-A51R2

Start date: July 2, 2020
Phase: Phase 1
Study type: Interventional

To evaluate a pharmacokinetic drug interaction between AJU-A51R1 and AJU-A51R2 in healthy male volunteers.

NCT ID: NCT04754334 Terminated - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

A Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus

Start date: March 16, 2021
Phase: Phase 3
Study type: Interventional

This double-masked placebo-controlled study will include approximately 450 subjects with inadequately controlled T2DM on diet control alone or on diet control and metformin monotherapy. Subjects will undergo an initial 21-day Screening Period, followed by a 26-week Double-Blind Treatment Period and a Double-Blind 26-week Treatment Extension Period.

NCT ID: NCT04706286 Not yet recruiting - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Clinical Trial to Investigate the Pharmacokinetics and Safety of CKD-393

Start date: February 18, 2021
Phase: Phase 1
Study type: Interventional

A Clinical Trial to evaluate the Pharmacokinetics and safety of CKD-393 0.5/100/1000 mg under fed condition

NCT ID: NCT04688359 Completed - Clinical trials for Cardiovascular Risk Factor

Effectiveness of Nurse-coordinated Follow-up Program in Primary Care for People at Risk for T2DM

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Previous Icelandic studies regarding prevalence of diabetes have mostly used data from the capital area. Information on the proportion of people at risk at developing T2DM or having undiagnosed T2DM among people living in rural Northern Iceland is unknown. Clinical guidelines recommend that patients with prediabetes (diabetes warning signs) should be referred to a counselling program. The study will evaluate effectiveness of nurse-coordinated Guided Self-Determination (GSD) follow up program toward health promotion, for people at risk of T2DM.

NCT ID: NCT04682795 Recruiting - Clinical trials for T2DM (Type 2 Diabetes Mellitus)

Comparison of Safety and Efficacy of Needle-Free Injector and Insulin Pen in Patients With T2DM

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

In this prospective, multi-center, randomized, open-label, parallel group trial, the safety and efficacy of needle-free injector will be compared with insulin pen after 2 weeks of treatment in patients with type 2 diabetes. This trial will enable assessment of the clinically relevant endpoint of a change in Time in Range (TIR), a newly recommended measurement of blood glucose fluctuations.