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Clinical Trial Summary

To explore the safety, tolerability, and clinical effects of decitabine combined with Second-line chemotherapy regimens for patients with relapsed or refractory T-lymphoblastic lymphoma.


Clinical Trial Description

This is a prospective, open,investigator initial clinical trial with a single arm, aimed to evaluate the safety, tolerability, and efficacy of decitabine combined with Second-line chemotherapy regimens (CODOX-M/IVAC) in relapsed or refractory T-lymphoblastic lymphoma. A total of 40 patients are planned to be enrolled into the study. Patients with diagnosis of relapsed or refractory T-lymphoblastic lymphoma will be treated with decitabine plus CODOX-M/IVAC. The primary end point is responder rate (RR) and time to progression (TTP), and the secondary end points include overall survival (OS) and the median survival time (MST). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03558412
Study type Interventional
Source Zhengzhou University
Contact Mingzhi zhang, Pro,Dr
Phone 13838565629
Email Mingzhi_zhang@126.com
Status Recruiting
Phase Phase 4
Start date June 1, 2018
Completion date June 1, 2020

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