Clinical Trials Logo

Clinical Trial Summary

The main aim of this study is to describe how effective and safe the re-treatment of adults with cutaneous T-cell lymphoma (CTCL) with brentuximab vedotin is. Another aim is to describe treatment patterns of persons with CTCL who have received brentuximab vedotin again. No treatment will be provided during this study. Information already existing in the participants' medical charts will be reviewed and collected.


Clinical Trial Description

This is a non-interventional, retrospective study of participants from France, Germany, Spain and Italy with CTCL who were retreated with brentuximab vedotin (BV) after a relapse in at least two different lines of therapy. The participants will be identified from their medical charts and those who meet the eligibility criteria will be included. The study will enroll approximately 50 participants. This multi-center trial will be conducted in Europe. The participants are assessed after the last dose of BV for approximately 4 months and followed up for at least 12 months after the re-treatment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05886478
Study type Observational
Source Takeda
Contact Takeda Contact
Phone +1-877-825-3327
Email medinfoUS@takeda.com
Status Recruiting
Phase
Start date February 8, 2024
Completion date June 30, 2024

See also
  Status Clinical Trial Phase
Completed NCT00959686 - Bendamustine in Patients With Refractory or Relapsed T-cell Lymphoma Phase 2
Active, not recruiting NCT04712864 - Study of CD4-Targeted Chimeric Antigen Receptor T-Cells (CD4- CAR-T) in Subjects With Relapsed or Refractory T-Cell Lymphoma Phase 1
Recruiting NCT05665530 - A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib in Participants With R/R Hematologic Malignancies Phase 1
Completed NCT01941680 - High Risk Adult T-cell Leukemia/Lymphoma (ATLL-HR) and Allogeneic Transplant
Recruiting NCT05075460 - Tucidinostat, Azacitidine Combined With CHOP Versus CHOP in Patients With Untreated Peripheral T-cell Lymphoma Phase 3
Completed NCT03734601 - Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation Phase 2
Completed NCT02017613 - Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in Hematological Malignancies Phase 1
Enrolling by invitation NCT01854112 - Helical Irradiation of Total Skin (HITS) for T Cell Lymphoma N/A
Completed NCT01553786 - Efficacy of a Treatment With CHOP and Lenalidomide in First Line in Angioimmunoblastic T-cell Lymphoma (AITL) Phase 2
Completed NCT00542919 - A Study for Patients With Non-Hodgkin's Lymphomas Phase 2
Recruiting NCT06131801 - Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
Active, not recruiting NCT03952078 - A Dose Escalation Study Evaluating CPI-818 in Relapsed/Refractory T-Cell Lymphoma Phase 1
Not yet recruiting NCT05983965 - Study of Tazemetostat in Lymphoid Malignancies Phase 1
Not yet recruiting NCT05387226 - Intravenous Injection of Oncolytic Virus Injection (RT-01) in Patients With Relapsed or Refractory T-cell Lymphoma Phase 1
Completed NCT02424045 - Bendamustine, Carboplatin and Dexamethasone (BCD) for Refractory or Relapsed Peripheral T-cell Lymphoma Phase 2
Completed NCT01871675 - Study of IPI-145 in Combination With Rituximab or Bendamustine/Rituximab in Hematologic Malignancies Phase 1
Terminated NCT00893516 - CD4 in Combination With CHOP in Treating Non-cutaneous Peripheral TCell Lymphoma Phase 2
Completed NCT01902225 - Phase I Dose-finding and Preliminary Efficacy Study of the Istodax® in Combination With Doxil® for the Treatment of Adults With Relapsed or Refractory Cutaneous T-cell Lymphoma Phase 1
Recruiting NCT02086591 - A Phase II Study of Doxycycline in Relapsed NHL Phase 2
Recruiting NCT04264078 - Anti-CD7 U-CAR-T Cell Therapy for T/NK Cell Hematologic Malignancies Early Phase 1