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Progressive Resisted Exercise Plus Aerobic Exercise on Osteoporotic Systemic Lupus Erythmatosus

Systemic Lupus Erythematosus Clinical Trial

Official title:
Progressive Resisted Exercise Program Combined With Aerobic Exercise on Osteoporotic Systemic Lupus Erythmatosus Patients, Randomized Controlled Trial

Clinical Trial Summary

systemic lupus erythematosus (SLE) is the most common autoimmune disease in women of childbearing age. Promoting physical activity is a major national priority for the general population, including patients with chronic diseases. The aim of this study is to investigate the efficiency of combined effect of progressive resisted exercise with aerobic exercise for bone mineral density, quality of life, muscle strength and physical activity for patients with SLE.

Clinical Trial Description

The following factors were found to be significantly related to lower BMD by univariate analysis: Caucasian race, older age at diagnosis, higher age at the time of the first DXA, longer disease duration, higher cumulative corticosteroid dose, lower serum levels of 25(OH)D, higher SLE Damage Index score, and postmenopausal status. In the multivariate analysis only the following factors were significant: Caucasian race, increased number of pregnancies, postmenopausal status, higher SLE Damage Index, and higher cumulative corticosteroid dose. As the quality of life among patients with SLE not fully associated with SLE disease activity, pharmacologic treatments that are effective for SLE disease activity might not be able to improve quality of life in these patients Therefore, the beneļ¬t of nonpharmacological therapies on quality of life has been explored. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05392790
Study type Interventional
Source Cairo University
Contact Nesma M Allam, PhD
Phone 00201281968332
Email dr.nesma2011@yahoo.com
Status Recruiting
Phase N/A
Start date May 23, 2022
Completion date December 30, 2023
View Details
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