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Clinical Trial Summary

The purpose of this study was to explore the clinical and immunological efficacy of belimumab plus low dose IL-2 in systemic lupus erythematosus.


Clinical Trial Description

Given that belimumab and low dose interleukin-2 (IL-2) have been widespreadly applied in the treatment of systemic lupus erythematosus (SLE), this study designed a randomised, single center, prospective study to investigate the effects and safety of combined utilization of belimumab and low dose IL-2. SLE patients were allocated in each group randomly (n=10) and regularly administered belimumab (10mg/kg) with or without IL-2 (1 million IU). Then, we evaluated the improvement of clinical and laboratory indexes and monitored the changes of immune cell subsets and cytokines. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05262686
Study type Interventional
Source Peking University People's Hospital
Contact Ruiling Feng
Phone +86 18952390737
Email jsfeng001224@163.com
Status Recruiting
Phase Phase 3
Start date April 1, 2022
Completion date June 1, 2023

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