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Systemic Fungal Infections clinical trials

View clinical trials related to Systemic Fungal Infections.

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NCT ID: NCT02968134 Completed - Clinical trials for Systemic Fungal Infections

Single Dose Population Pharmacokinetics of Intravenous Posaconazole in Critically Ill Patients

POSA
Start date: January 16, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to try to find out how critically ill patients receiving the anti fungal medication, posaconazole, process it in their body. Investigators would like to study if the recommended doses of posaconazole achieve adequate concentrations in the patients blood to treat fungal infections.The disease process in critically ill patients can profoundly influence the concentration of anti fungal medication in the blood. The process by which a drug travels through the body in blood, how it is broken down and removed by the body is called pharmacokinetics (PK). This information is important to know because if antifungal levels are low in the blood, the fungal infection has an opportunity to become resistant to the antifungal medication which can lead to the medication being less effective against the fungal infection potentially exposing future patients with infection to a limited range of effective antifungals. Investigators can measure the PK by taking blood samples at specific times after the anti fungal medication is given. This study will enroll 8 patients who are admitted to the intensive care unit and are being treated with an antifungal medication for a fungal infection. Patients will be consented and given a single dose of posaconazole and serial blood samples will be collected just prior to the dose and at 15, 45,75 minutes during the infusion and at 3, 5, 8, 12, 18, 24, 30 36 and 48 hours . Information about the patients stay in the ICU will also be collected including blood pressure, temperature, blood test results.

NCT ID: NCT01686607 Completed - Clinical trials for Systemic Fungal Infections

Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents

MYCOS
Start date: October 1, 2012
Phase:
Study type: Observational

This multicenter observational cohort study proposes to establish the risks of short and long-term outcomes in users of parenteral micafungin and in users of other parenteral antifungal agents from 2005 through 2012 with follow-up until 2017.

NCT ID: NCT00721578 Completed - Clinical trials for Systemic Fungal Infections

A Study Of Indian Patients Receiving Therapy For Systemic Fungal Infections

Start date: April 2009
Phase: N/A
Study type: Observational

To collect and summarize information on the diagnosis, management, and clinical and mycological outcomes of patients with systemic fungal infections in order to better understand the effectiveness of antifungals in the treatment of Systemic Fungal Infections (SFI) in India.