Syphilis Clinical Trial
Official title:
Evaluation of the Sensitivity, Specificity, and Utility of the Reveal® TP (Syphilis) Antibody POCT to Diagnose Infectious Syphilis in Participants Attending the BCCDC's STI Clinic in Vancouver, BC
This study is to test the Reveal® TP (Syphilis) antibody POCT (MedMira, Inc., Halifax, Nova Scotia) for its performance in an urban STI clinic in Vancouver, British Columbia and compare its performance in parallel with the usual testing method (the gold standard).
This study is to test the Reveal® TP (Syphilis) antibody POCT (MedMira, Inc., Halifax, Nova Scotia) for its performance in an urban STI clinic in Vancouver, British Columbia and compare its performance in parallel with the usual testing method (the gold standard). The healthcare professional will advise patients about the study, and with their permission refer them to research staff for recruitment. Should patients choose to participate in the study they will be asked to provide consent to have a few drops of blood sample obtained through a finger prick to be used in the POCT. POCT results will not be provided to participants and this will be explained in both the recruitment script and informed consent form. A sample of 5 to 10 ml venous whole blood will also be obtained for the conventional syphilis serology testing which is part of the routine for care of the four categories of patients (regardless of this research). This research will take approximately 15 to 30 minutes and will be on top of the regular care that patients will receive in the clinic. Upon completing the tests, participants will be asked to complete a brief feedback survey to assess patients' acceptability of syphilis POCT. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03660488 -
Cefixime for Alternative Syphilis Treatment
|
Phase 2 | |
| Recruiting |
NCT05548426 -
Linezolid for Syphilis Pilot Study
|
Phase 2 | |
| Completed |
NCT02191527 -
Evaluating the Effectiveness of Point-of-care Diagnostic Technologies in MCH Services in Mozambique
|
N/A | |
| Completed |
NCT01439503 -
Safer Sex Program for Young African-American Men
|
Phase 2 | |
| Terminated |
NCT01540227 -
Penicillin Therapeutic Drug Monitoring in the Treatment of Infectious Syphilis.
|
||
| Completed |
NCT02257658 -
Efficacy of Doxycycline Prophylaxis to Reduce Syphilis in High-Risk, HIV-Positive MSM
|
N/A | |
| Completed |
NCT02611765 -
Syphilis Response to Higher Penicillin Dosage: The 2.4 Versus 7.2 Study
|
Phase 4 | |
| Not yet recruiting |
NCT06428643 -
A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities
|
N/A | |
| Completed |
NCT03709862 -
Global Syphilis Sequencing
|
||
| Completed |
NCT03637660 -
Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection
|
Phase 4 | |
| Active, not recruiting |
NCT03310424 -
Transcriptomic and Next Generation Sequencing Approaches to Infection With Treponema Pallidum
|
||
| Completed |
NCT00207506 -
Lay Health Advisors for Sexually Transmitted Disease Prevention
|
Phase 1/Phase 2 | |
| Completed |
NCT00213018 -
Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing HIV/STI Transmission
|
Phase 2 | |
| Recruiting |
NCT06059443 -
mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention
|
N/A | |
| Completed |
NCT04480749 -
Syphilis Self-testing to Expand Test Uptake Among Men Who Have Sex With Men (SST)
|
Phase 4 | |
| Not yet recruiting |
NCT06058286 -
MENJAGA: Continuous Quality Improvement for Antenatal HIV, Syphilis and Hepatitis B Testing in Indonesia
|
N/A | |
| Active, not recruiting |
NCT03980223 -
Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With Men
|
Phase 4 | |
| Completed |
NCT01465607 -
Implementation of an Efficacious Intervention for High Risk Women in Mexico
|
N/A | |
| Completed |
NCT00553111 -
Video Tool to Promote Knowledge of Syphilis as Facilitator of HIV Transmission
|
N/A | |
| Active, not recruiting |
NCT06367621 -
Retrospective Study of iStatis Syphilis Ab Test (POC)
|