Clinical Trials Logo

Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT03507933
Other study ID # OBS-0033
Secondary ID
Status Recruiting
Phase
First received March 7, 2018
Last updated April 16, 2018
Start date January 30, 2018
Est. completion date June 2018

Study information

Verified date March 2018
Source Lille Catholic University
Contact Amélie Lansiaux, MD, PhD
Phone + 33 320225269
Email lansiaux.amelie@ghicl.net
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Villo-nodular synovitis can affect the joints, bursae or tendon sheaths. This condition is rare, with 1.8 cases per million inhabitants. The hip is affected in 3.6 to 18.1% of cases. The age of predilection is between 30 and 50 years old and this condition is rarely described in children.

Two articles report a case of villous-nodular synovitis of the child's hip. Surgical treatment by resection seems to be consensus but various adjuvant treatments are also proposed. A case of villous-nodular synovitis of the hip in children was treated without surgical intervention. The main objective of this study was to evaluate the efficacy of surgical treatment of villous nodular synovitis of the hip in children.


Description:

French multicentric cases serie


Recruitment information / eligibility

Status Recruiting
Enrollment 6
Est. completion date June 2018
Est. primary completion date June 2018
Accepts healthy volunteers
Gender All
Age group 10 Years to 18 Years
Eligibility Inclusion Criteria:

- Children with histologically villo-nodular synovitis of the hip

- Surgical procedures performed for the treatment of this synovitis

Exclusion Criteria:

- Degree of bone maturation and Risser test greater than 4 at the time of diagnosis

- Parents opposing the use of their child's data / Patient opposing the use of his/her data

Study Design


Related Conditions & MeSH terms

  • Synovitis
  • Synovitis, Pigmented Villonodular

Locations

Country Name City State
France Lille Catholic University Lille

Sponsors (1)

Lead Sponsor Collaborator
Lille Catholic University

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary Change from baseline in the range of motion of the hip in degrees Evaluation of extension / flexion / abduction / adduction / external rotation / internal rotation of the hip before surgery and 4 months after surgery
Primary Incidence of signal changes in the X-Ray 4 months after surgery
Primary Incidence of signal changes in the MRI 4 months after surgery
Secondary Change from baseline in the scale measure of patient's pain intensity before surgery and 4 months after surgery
Secondary Incidence of complications after surgery 4 month after surgery
Secondary Number of additional treatments used in addition to surgery Frequency of adjuvant treatments 4 month after surgery
Secondary Change from baseline in the physical activity evaluated by a questionnaire yes /no questionnaire before surgery and 4 months after surgery
See also
  Status Clinical Trial Phase
Completed NCT01272830 - Double-Blinded Clinical Trial Using Apatone®B for Symptomatic Postoperative Total Joint Replacements Phase 2
Completed NCT04750993 - Comparison of the Frequency of Subclinic Synovitis in the Distal Interphalangeal Joints of the Hand in Psoriasis Patients
Not yet recruiting NCT01731262 - Preliminary Study of Sonic Hedgehog Signaling Pathway in the Pathogenesis of Rheumatoid Arthritis N/A
Enrolling by invitation NCT04641351 - Corticosteroid Meniscectomy Randomized Trial Phase 4
Not yet recruiting NCT05700682 - Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee
Completed NCT02403687 - Prospective Analgesic Compound Efficacy (PACE) Study N/A
Completed NCT00001677 - Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy Phase 2
Recruiting NCT05629130 - Embolization in Hereditary Coagulopathies N/A
Completed NCT00604539 - Effect of Chondroitin Sulphate on Synovial Inflammation in Patients With Osteoarthritis of the Knee Phase 3
Terminated NCT02060305 - Intra-articular Bevacizumab for Recurrent Hemarthroses at Target Joints With Chronic Hemophilic Synovitis Phase 1
Completed NCT02902562 - Synovitis and Therapy Response in Inflammatory Arthritis With Contrast Enhanced Ultrasound N/A
Completed NCT00001679 - Prognostic Indicators and Determinants of the 2-5 Year Outcome in a Cohort of Early Synovitis Patients N/A
Completed NCT00001375 - The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis N/A
Recruiting NCT00903903 - Computer-Assisted Quantification of the Synovial Perfusion in Patients With Arthritis Using Two-Dimensional and Three-Dimensional Power Doppler Ultrasonography N/A
Completed NCT00890058 - A Case Control Study to Define Clinical, Immunologic and Radiographic Features of the Aromatase Inhibitor Arthralgia Syndrome N/A
Recruiting NCT06352216 - Prevalence of Synovitis in Patients With Haemophilia A