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Sweating clinical trials

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NCT ID: NCT05586477 Completed - Allergic Rhinitis Clinical Trials

Diphenhydramine and Sweating

BENEXE2022
Start date: November 21, 2022
Phase: Phase 4
Study type: Interventional

In 2012, it was estimated that nearly 1 in 4 Canadians suffer from allergic rhinitis. To add, 78% of individuals working in predisposing environments are predicted to develop occupational rhinitis. Currently, the most popular treatment for rhinitis is antihistamine medication such as diphenhydramine, a first-generation antihistamine sold commercially as Benadryl®. Due it its anticholinergic effects, diphenhydramine has been suggested to impair the whole body sweating response during heat stress, potentially leaving consumers at an increased risk of heat-related illness. This randomized control trial approved by Health Canada will investigate whether ingesting extra strength diphenhydramine (50mg) will alter whole-body sweat losses during 60 minutes of exercise.

NCT ID: NCT00335478 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Daptomycin in Treating Neutropenia and Fever in Patients With Cancer

Start date: December 2006
Phase: Phase 2
Study type: Interventional

RATIONALE: Antibiotics, such as daptomycin, may control neutropenia, fever, and infection in patients with cancer. PURPOSE: This phase II trial is studying how well daptomycin works in treating neutropenia and fever in patients with cancer.