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Swallowing Disorder clinical trials

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NCT ID: NCT05484726 Recruiting - Preterm Birth Clinical Trials

Maternal Role in Oral Feed Establishment in Preterm Neonates

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Hypothesis Preterm babies who receive sensory motor stimulation from their mothers as compared to trained nurses will 1. Start taking oral feed at the same time as compared to control group 2. Take the same amount of milk at the commencement of oral feeding 3. Take milk with equal efficiency 4. Not face more adverse effects

NCT ID: NCT05337475 Recruiting - Swallowing Disorder Clinical Trials

Feeding and Swallowing Problems in Infants With Laryngomalacia

Start date: April 1, 2022
Phase:
Study type: Observational

Observational cross-sectional study Infants with laryngomalacia Feeding and swallowing assessment

NCT ID: NCT04584658 Recruiting - Covid19 Clinical Trials

Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)

DYADS
Start date: September 15, 2020
Phase:
Study type: Observational

This study examines the presence, severity and natural history of dysphagia and dysphonia in the post-extubation and severely unwell COVID-19 patient.

NCT ID: NCT04581486 Recruiting - Malnutrition Clinical Trials

Effectiveness of an Optimal-Massive Intervention in Older Patients With Dysphagia

OMI
Start date: June 6, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of an optimal-massive intervention (OMI) based on increasing shear viscosity of fluids, nutritional support with oral nutritional supplements (ONS) and triple adaptation of food (rheological and textural, caloric and protein and organoleptic) and oral hygiene improvement on the incidence of respiratory infections in older patients with OD. We have designed a randomized clinical trial, with two parallel arms and 6 months follow-up. The study population will be constituted by older patients of 70 years or more with OD hospitalized at Hospital de Mataró by an acute process that will be identified by using the volume-viscosity swallow clinical test. We will consecutively recruit 500 subjects during admission (Geriatrics, Internal medicine, etc.) at the Hospital de Mataró. Patients included will be randomly assigned to one of both interventional groups: a) study intervention: multifactorial intervention based on fluid viscosity adaptation (with a xanthan gum thickener -> Nutilis Clear®), nutritional support with a triple adaptation of food (texture, caloric and protein content, organoleptic) + pre-thickened ONS and evaluation and treatment of oral hygiene (tooth brushing + antiseptic mouthwashes + professional dental cleaning), or b) control intervention: standard clinical practice (fluid adaptation with Nutilis Powder and simple texture adaptation for solids). Main outcome measures: respiratory infection incidence during the 6-month period follow-up. Secondary outcomes: mortality at 6 months, general hospital readmissions and readmissions due to respiratory infections, nutritional status, hydration status, quality of life, functional status, oral hygiene and dysphagia severity and its relationship with other study variables.

NCT ID: NCT04565587 Recruiting - Dysphagia Clinical Trials

Dose-response Effect of the Thickener Tsururinko Quickly

58/19
Start date: August 5, 2020
Phase: N/A
Study type: Interventional

Thickening fluids are a valid therapeutic strategy to improve safe swallowing in OD. The aim of this study is to assess the percentage of safe swallowing at different viscosity levels thickened with Tsururinko Quickly. This study is designed to assess the therapeutic effect on safety and efficacy of swallow of Tsururinko Quickly for the levels of viscosity 100, 200, 400, 800, 1600mPa·s against thin liquid and between all the viscosity levels in older patients with Oropharyngeal Dysphagia (OD) by performing a Videofluoroscopy when swallowing. As all patients will start with thin liquid, each patient will be its own control. To analyze the effect of the salivary amylase on the thickener, participants will be asked to maintain two boluses (200 and 800mPa·s) prepared jut with mineral water in the oral cavity for 30seconds. After that period, boluses will be analyzed by a viscometer and compared to those without oral incubation.

NCT ID: NCT03306134 Recruiting - Swallowing Disorder Clinical Trials

The Effect of Beta-blockers in Substance P Levels and the Swallowing Function

BETASP
Start date: June 5, 2017
Phase: N/A
Study type: Observational

A non-randomised, prospective study to assess the effects of beta-blockers on substance P levels and the swallowing function. The study is going to be carry out in the Gastrointestinal Physiology Laboratory of the Hospital de Mataró (Spain). All participants will be actively recruited from a Linked hospital and primary care database. We include two groups: the first group (group 1) are participants taking beta-blockers and the second group (group 2) are participants not-taking beta-blockers.

NCT ID: NCT01268423 Recruiting - Swallowing Disorder Clinical Trials

Early Percutaneous Tracheostomy and Swallowing Dysfunction

Start date: January 2011
Phase: Phase 3
Study type: Interventional

The aim of the study is to determine if performing an early tracheostomy (within the first 4 days of endotracheal intubation) in critically ill patients on mechanical ventilation, reduces the incidence of swallowing dysfunction.