Aspiration of Gastric Contents Into Respiratory Tract, Part Unspecified Clinical Trial
Official title:
Comparison on Succinylcholine Onset Time Assessed by Train of Four Stimulation Versus Clinical Judgment During Rapid Sequence Induction
Succinylcholine is a myorelaxant agent often used during rapid sequence induction for
patients who need to undergo general anesthesia but who are at risk of pulmonary aspiration
of gastric content. Whereas other myorelaxant agents are monitored with train of four
stimulation to assess onset and duration, few anesthesiologists use train of four stimulation
for onset of succinylcholine, as the anesthesiologists evaluate the effect with the time from
injection (usually one minute) and the muscle fasciculation due to the release of
acetylcholine.
The data available on onset duration of this drug are old and bases on only few studies, but
the succinylcholine if sometime harmful (anaphylaxis , cardiac arrest, bronchospasm).
The investigators want to assess the onset time of succinylcholine with an objective toll ,
the train of four stimulation, and evaluate if the clinical judgment of the anesthesiologist
is reliable to predict an adequate moment for endotracheal intubation.
n/a