Assessment of Functional Capacity, Pain, Cognitive and Respiratory Functions in Lung Cancer Survivors

Survivorship Clinical Trial

Official title:

Assessment of Functional Capacity, Pain, Cognitive and Respiratory Functions in Lung Cancer Survivors

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04431921
• Other study ID #: GO17/555
• Status: Completed
• Start date: July 17, 2017
• Est. completion date: June 1, 2018

Study information

• Verified date: June 2020
• Source: Hacettepe University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Serious side effects occurs with disease and treatments in survival after lung cancer. For this reason, functional capacity, cognitive status, pain perception and respiratory functions may be affected in lung cancer. The purpose of this study was to evaluate respiratory function, respiratory muscle strength and endurance, functional capacity, pain, cognitive status level, and physical activity in lung cancer patients and compare with the findings of healthy subjects

Description:

This study was participated lung cancer patients survivors. Patients' pulmonary function test, functional capacity, respiratory muscle strength and endurance, pain and cognitive status was assessed and recorded.

Pulmonary function testing (PFT), mouth pressure measurement (MIP- maximal inspiratory pressure and MEP- maximal expiratory pressure), respiratory muscle endurance test, six minute walk test (6MWT) and pain threshold and tolerance test were used. In addition to physiological measurements, the Montreal Cognitive Assessment (MoCA) scale was used to evaluate cognitive status, the International Physical Activity Questionnaire (IPAQ) was used to determine the level of physical activity.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: June 1, 2018
• Est. primary completion date: June 1, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 45 Years to 80 Years

Eligibility

Inclusion Criteria:

• Cooperation

• lung cancer patients who had a stable condition

Exclusion Criteria:

• Active cancer treatments

• Brain metastasis story

• Any orthopedic disease impairs walking, balance

Related Conditions & MeSH terms

• Lung Neoplasm
• Lung Neoplasms
• Survivorship

Intervention

Diagnostic Test:
• Functional capacity
Six minute walk test used assessment of functional capacity. For respiratory function mouth pressures, for cognitive functions MoCA scale and for pain assessment pain threshold and tolerance test assessed.

Locations

Country	Name	City	State
Turkey	Hacettepe University	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Hacettepe University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Functional capacity	Six minute walk test: Distance walked in six minute was recorded	15 minutes
Secondary	Respiratory muscle strength assessment	Respiratory muscle strength was evaluated by measuring maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP).	10 minutes
Secondary	Respiratory muscle endurance	Pressure time unit: A constant load test was used to evaluate respiratory muscle endurance. Using a PowerBreathe device (HaB International Ltd., Southam, UK), the participants were asked to breathe maintaining a constant threshold (60% of MIP) until task failure, and the test duration was recorded. Results were obtained by multiplying the set pressure by the test duration	10 minutes
Secondary	Pulmonary functions test	pulmonary functions assessment via spirometry	15 minutes
Secondary	Cognition using MoCA-Test	Cognitive function was evaluated with the secreening tool the Montreal Cognitive Assessment (MoCA). The MoCA is a 30-point screening tool. Higher scores mean a better outcome.	10 minutes
Secondary	Pressure pain threshold assessment	Pressure pain threshold was evaluated via algometer. The pressure at which the individual first reported pain was recorded.	15 minute
Secondary	Pressure pain tolerance assessment	Pressure pain tolerance test was evaluated via algometer.The pressure at which the individual last pressure point at which they could endure the pain was recorded.	15 minute
Secondary	Physical activity level	International Physical Activity Questionnaire-Short Form	5 minutes