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Surgical Wound Infection clinical trials

View clinical trials related to Surgical Wound Infection.

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NCT ID: NCT04250961 Completed - Clinical trials for Surgical Wound Infection

Effects of Showering in 48-72 Hours of Median Sternotomy on Wound Infection, Pain, Comfort and Satisfaction

Start date: December 21, 2016
Phase: N/A
Study type: Interventional

Time of showering after surgery is still a controversial issue for surgical patients and health professionals. It has been reported that patients should not shower until sutures are removed since traditionally showering is thought to cause infections after surgery. However, not showering after surgery not only has a negative effect on patient comfort but also brings about the risk of infections. Sternal wound infections after coronary artery bypass graft surgery through median sternotomy are one of the important, life-threatening complications. For this reasons, the investigators researched the advantages and disadvantages of showering for postoperative sternal wound infections, pain due to sternotomy and patient comfort and satisfaction.

NCT ID: NCT04233424 Completed - Clinical trials for Surgical Site Infection

D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection

Start date: June 24, 2020
Phase: Phase 3
Study type: Interventional

Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to assess Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care (SoC), compared to a SoC treated control arm, in prevention of post abdominal surgery incisional infection.

NCT ID: NCT04218110 Completed - Clinical trials for Surgical Site Infection

Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances

Start date: February 11, 2020
Phase: Phase 3
Study type: Interventional

Comparative study of antimicrobial effectiveness evaluation of of 26ml Project X, 10.5ml Project X, 5.1ml Project X and Prevantics Maxi swabstick following ASTM E1173 - Standard test method for evaluation of preoperative, precatheterization or preinjection skin preparations.

NCT ID: NCT04146116 Completed - Clinical trials for Surgical Site Infection

Nasal Decolonization for Orthopedic Trauma Patients

Start date: February 19, 2020
Phase: Phase 4
Study type: Interventional

Many surgical site infections are caused by bacteria that is transferred from a patient's nose to their open surgical wound. Some small studies have shown that putting povidone-iodine in a patient's nose reduces this risk. This study aims to evaluate the real-world effectiveness of nasal povidone-iodine (PROFEND®) in a group of 50 patients at the University of Iowa.

NCT ID: NCT04129177 Completed - Clinical trials for Colorectal Neoplasms

Reduction of Surgical Site Infections in Elective Colorectal Surgery After the Implementation of a Bundle of Care.

Start date: October 1, 2018
Phase:
Study type: Observational [Patient Registry]

Background. The Nosocomial Infection Surveillance Program in Catalonia (VINCat) monitors SSI in elective colorectal surgery since 2007 in 56 hospitals (7.5 million population). These hospitals perform active and prospective standardized surveillance of elective colorectal resections. Post-discharge surveillance is mandatory up to 30 days after surgery. Between 2007 and 2015, the SSI rate did not change significantly, with a cumulated incidence of 5,491 SSI in a total of 29,006 interventions (19%). In 2015, a working group of VINCat specialists and surgeons from the Catalan Society of Surgery was set up to formulate a specific bundle of SSI preventative measures for colorectal surgery. Aim. To analyse the effect of a specific bundle for SSI prevention in elective colorectal surgery. Methods. In 2016, a bundle of six preventative measures was recommended to the VINCat hospitals. Bundle measures were: systemic and oral antibiotic prophylaxis, mechanical bowel preparation (MBP), laparoscopic surgery, maintenance of normothermia, and the use of a double-ring wound retractor. The results of SSI before and after the implementation of the bundle are compared. The results are analysed using the chi-square test (statistical significance p <0.05).

NCT ID: NCT04088162 Completed - Surgical Wound Clinical Trials

The Use of Post-operative NPWT Dressing in the Prevention of Infectious Complications After Ostomy Reversal Surgery

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Introduction: Although negative-pressure wound therapy (NPWT) is likely advantageous for wound healing, the efficacy and safety of its prophylactic use remain unclear. We performed a Randomized Control Trial to assess the usefulness of postoperative NPWT in reduction of postoperative wound healing complications and surgical site infections after diverting ileostomy closure, in the group of patients previously operated for colorectal resection due to cancer. Materials & Methods: Prospective, randomized study will be conducted. Patients with past history of colorectal cancer laparoscopic surgery with protective loop ileostomy scheduled to undergo ileostomy closure with primary wound closure will be randomly divided into groups with or without NPWT. The primary endpoint are incidence of wound related complications (WRC) (wound healing complications witch required surgical intervention other than suture removal or dressing changing). The secondary endpoints are incidences of Surgical Site Infection (SSI) and length of postoperative hospital stay (LOS) and length of complete wound healing (CWH). Cost analysis will also be performed. In first step of this study between January 2016 and December 2018 we will asses the usefulness of one of the NPWT devices (NANOVA KCI) in prevention of WHC in established group. The second part of the study will be performed in 2 centers between January 2019 and December 2021. In this step we want to compere other NPWT devices in the same application and to confirm single center outcomes .

NCT ID: NCT04067843 Completed - Clinical trials for Surgical Site Infection

Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study

PHOMIC
Start date: September 26, 2019
Phase: N/A
Study type: Interventional

The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if photodynamic therapy has an effect on bacterial skin colonization and decrease number of colonizing bacteria associated with sebaceous and sweat glands in order to improve skin antisepsis strategies for the prevention of surgical site infections.

NCT ID: NCT04057092 Completed - Clinical trials for Surgical Site Infection

Perioperative Immunonutrition in Patients Undergoing Gynecologic or General Elective Surgery (PURPOSE)

PURPOSE
Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The objective of the implementation pilot is to assess the practicality of introducing a perioperative immunonutrition protocol into a hospital environment as well as a true measure of impact on the rate of surgical site infection (SSI).

NCT ID: NCT04055233 Completed - Clinical trials for Surgical Site Infection

Reduction of Postoperative Wound Infections by Antiseptica?

RECIPE
Start date: February 1, 2015
Phase: Phase 3
Study type: Interventional

Wound infections are a frequent complication in abdominal surgery. The investigators hypothesize that the antiseptic solution 0.04 % polyhexanide (serasept) may reduce occurrence of postoperative wound infections compared to NaCL (saline) solution in a prospective randomized setting.

NCT ID: NCT04048356 Completed - Clinical trials for Urinary Incontinence

Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures

CLNUP
Start date: July 15, 2019
Phase: Phase 3
Study type: Interventional

This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.