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Surgical Wound, Healed clinical trials

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NCT ID: NCT06190015 Active, not recruiting - Post Operative Pain Clinical Trials

Impact of Advanced Platelet Rich Fibrin and Enamel Matrix Derivative on Clinical and Molecular Wound Healing Parameters After Surgical Removal of Mandibular Third Molars

Start date: May 23, 2022
Phase: Phase 4
Study type: Interventional

Brief summary The goal of this study is to compare the effects of advanced platelet rich fibrin and enamel matrix derivative placed in the extraction alveoli of patients who had surgical removal of mandibular wisdom teeth. The questions it aims to answer/evaluate are: - postoperative pain, swelling, trismus, early wound healing using soft tissue healing index - level of early local inflammatory response by measuring levels of inflammatory mediators in wound exudate - degree of wound healing by measuring levels of early wound healing mediators in wound exudate - incidence of alveolar osteitis and delayed infection - levels of probing depth, clinical attachment loss, gingival margin level, bleeding on probing, gingival index, plaque index of the second mandibular molar 3 months after surgery Participants of the study will be asked: - for their preoperative clinical measurements (swelling, trismus, periodontal parameters) to be taken by the principal investigator - to provide 20 ml of venous blood if necessary - to preoperatively provide gingival crevicular fluid in the region of distal surface of the second mandibular molar and postoperatively wound exudate - to note the number of painkiller pills taken after surgery and pain levels in different time points - to come to regular checkups in which clinical measuring of postoperative swelling, trismus levels and periodontal parameters will be performed

NCT ID: NCT05716490 Completed - Clinical trials for Surgical Site Infection

Optimizing Closed Incision Negative Pressure Wound Therapy in Emergency Laparotomy

OPTIWOUND
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to find differences in rates of surgical site infections following emergency laparotomy with the use of two different incisional negative pressure wound therapy (iNPWT)devices.

NCT ID: NCT04407364 Recruiting - Clinical trials for Surgical Wound, Healed

MPM Medical CoMatryx Surgical Bovine Collagen Study

Start date: September 2, 2020
Phase:
Study type: Observational

The objective of this prospective enrollment study is to collect data confirming safety, performance and clinical benefits of the CoMatryx Surgical Collagen powder at a minimum 1-year follow-up and compare it to a historical control group who did not receive the product at the time of surgery. The primary objective is to confirm safety and clinical benefits of the product. This will be assessed by recording the rate of wound healing and incidence and frequency of wound care related complications. Relationship of complications to the product should be specified.

NCT ID: NCT04038671 Withdrawn - Clinical trials for Surgical Wound, Healed

Activated Carbon Interphase Effect on Surgical Incisions vs.Two Common Wound Dressings

Start date: January 7, 2019
Phase: N/A
Study type: Interventional

This randomized, prospective study evaluates incision closure, post-surgical wound complications, dressing changes, incision/scar appearance, pain associated with dressing changes, and patient satisfaction rates of an activated carbon dressing versus two commercially available wound dressings.