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Association of Cephalosporin Resistance and Surgical Site Infections in Patients Undergoing Pancreaticoduodenectomy

Surgical Site Infection Clinical Trial

Official title:
Association of Cephalosporin Resistance in Intraoperative Biliary Cultures With Surgical Site Infections in Patients Undergoing Pancreaticoduodenectomy - A Retrospective Cohort Study

Clinical Trial Summary

Preoperative biliary drainage predisposes the bile to be contaminated with bacteria of the duodenum. These bacteria colonizing the bile are a potential source for surgical site infections after pancreaticoduodenectomy and many international guidelines recommend the use of cephalosporines as microbial prophylaxis before surgery. The aim of this study was to assess the incidence of bacteria in bile, their resistance profiles and association to surgical site infections in relation to timing of surgery after preoperative biliary drainage in order to better guide antibiotic use.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05581017
Study type Observational
Source Helsinki University Central Hospital
Contact
Status Completed
Phase
Start date June 16, 2020
Completion date October 10, 2022
View Details
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