Surgical Procedure, Unspecified Clinical Trial
Official title:
Apneic Oxygénation by Nasal Canula During Infants Airway Management Study
This is a randomized clinical trial investigating the utility of apneic oxygenation via high flow nasal cannulae during airway management for infants general anaesthesia. Three groups will be compared, a control group at 0 L/min, a 0,2L/Kg/min and a 1L/Kg/min group. The primary outcome will be the time (in seconds) between onset of apnea and one of theses end-points : desaturation (SPO2 <95%) or Airway management completed.
Airway management can be a life saving therapy. One major complication that may occur during
airway management is a lack of oxygen in the blood, especially in peadiatric population, due
to anatomical and physiological considerations. If severe or prolonged, this lack of oxygen
can result in permanent brain damage, damage to other vital organs or even death.
Pre-oxygenation prior to induction of anaesthesia is standard practice to prevent
desaturation and hypoxemia. Apnoeic oxygenation in adults is effective and prolongs the time
to desaturation. Apneic oxygenation is a novel method of delivering oxygen to a patient
despite a lack of active respiration (i.e. the patient is not breathing on their own and the
investigators are not providing the patient an artificial breath). The simplest and least
invasive method to provide apneic oxygenation is the application of oxygen through nasal
cannula during airway management. The effectiveness of apnoeic oxygenation in the adult is
well document, especially in bariatric population or ICU, however only few study are
interesting about pediatric population. Recent studies suggest that high flow is similar to
low flow oxygenotherapy. Therefore, the aim of this study was to investigate the
effectiveness of apnoeic oxygenation during airway management in infants.
This is a randomized clinical trial investigating the utility of apneic oxygenation via high
flow nasal cannula during airway management for infant's general anesthesia. Three groups
will be compared, a control group at 0 L/min, a 0,2L/Kg/min and a 1L/Kg/min group. The
primary outcome will be the time (in seconds) between onset of apnea and one of these
end-points : desaturation (SPO2 <95%) or Airway management completed.
All infants included will receive french actual standard of care concerning general
anesthesia and peri-operative medicine.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03299920 -
Opioid Consumption After Knee Arthroscopy
|
N/A | |
| Completed |
NCT04061629 -
Minimal Occlusive Pressure With Cuffed ETTs: The Effect of 3 Different Sizes of cETT on Intracuff Pressure in Children
|
||
| Not yet recruiting |
NCT03213548 -
Aesthetic and Functional Results of Alar Base Modifications in Rhinoplasty
|
N/A | |
| Completed |
NCT06164158 -
Role of Procedural Videos in Teaching the Surgery Residents
|
N/A | |
| Recruiting |
NCT03854669 -
Experimental Pain Reporting Accuracy and Clinical Post-operative Pain
|
N/A | |
| Active, not recruiting |
NCT03776591 -
Open D3 Right Hemicolectomy Compared to Laparoscopic CME for Right Sided Colon Cancer
|
N/A | |
| Completed |
NCT04332679 -
Non-resorbable Membranes Versus Titanium Meshes and Resorbable Membranes
|
N/A | |
| Completed |
NCT03305666 -
Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures
|
Phase 4 | |
| Completed |
NCT05008107 -
Virtual Reality as a Perioperative Teaching Tool for Families
|
N/A | |
| Terminated |
NCT02399111 -
A Trial to Evaluate Negative Pressure Incision Management System for Groin Wounds in Vascular Surgery Patients
|
N/A | |
| Terminated |
NCT00753766 -
Multifactorial Pre-operative Intervention in Diabetes Mellitus
|
N/A | |
| Active, not recruiting |
NCT03684720 -
Using 'Guided-Discovery-Learning' to Optimize and Maximize Transfer of Surgical Simulation
|
N/A | |
| Recruiting |
NCT04134975 -
Evaluation of the Contribution of Intraoperative Scans Coupled With the Navigation for the Precision of the Positioning of the Pedicle Screws During a Lumbar Spine Surgery: a Prospective Randomised Study
|
N/A | |
| Completed |
NCT06148701 -
Preoperative Anesthesia Automatic System:a Retrospective Cohort Study
|
||
| Active, not recruiting |
NCT04202874 -
A Trial Comparing Surgeon-administered TAP Block With Placebo After Midline Laparotomy in Gynecologic Oncology
|
Phase 3 | |
| Completed |
NCT05428579 -
Status of Surgical Resection and Histologic Subtype as Predictors of Local Recurrence in Retroperitoneal Liposarcoma
|
||
| Completed |
NCT02626546 -
Predictors, Risk Factors and Outcome Following Major Surgery
|
||
| Recruiting |
NCT06278610 -
Pelvic Exenteration and Laterally Extended Pelvic Resection
|
||
| Recruiting |
NCT05044832 -
Decreasing Emergence Agitation With Personalized Music
|
N/A | |
| Completed |
NCT04327895 -
Surgery in Context of Terrorist Attack : a Survey of French Surgeons
|