Clinical Trials Logo
  1. Home
  2. Surgical Procedure, Unspecified
  3. NCT03556696

Automatic Remifentanil Administration Guided by ANI During Propofol Anesthesia — ANI-LOOP  

Surgical Procedure, Unspecified Clinical Trial

Official title:
Automatic Remifentanil Administration Guided by the Analgesia Nociception Index During Propofol Anesthesia

Clinical Trial Summary

Prospective Randomized Monocentric Clinical Trial during propofol anesthesia. The aim of the study is to test whether the use of a medical device designed to automatically administer remifentanil during surgery based on expert rules and continuous reading of heart rate, blood pressure and the Analgesia Nociception Index results in lower overall remifentanil administration versus standard practice.

Clinical Trial Description

Prospective Randomized Monocentric Clinical Trial during propofol anesthesia. - inclusion: ASA 1, 2 or 3 adult patients scheduled to undergo burn wound surgery in a Burn Center (University Hospital of Lille, France) - arm 1 : Remifentanil will be automatically administered by an expert system guided by heart rate, blood pressure and the Analgesia Nociception Index (ANI). - arm 2 : Remifentanil will be administered by a target controlled device using the Minto pK/pD model. - propofol is administered throughout the procedure with a target controlled device using the pK/pD model of Schnider. The target will be guided by the BiSpectral index values. - primary endpoint : overall normalized remifentanil administration. - secondary endpoints : relative amount of time spent in a state of hemodynamic reactivity ; relative amount of time the ANI spends in the [0-50], [50-70] and [70-100] windows ; relative amount of time the BIS spends in the [0-40], [40-60] and [60-100] ; hemodynamic status at various times during anesthesia ; total amount of target modifications of remifentanil and propofol ; total amount of morphine administered in PACU ; total amount of ketamine administered in PACU ; incidence of nausea/vomiting in PACU ; ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03556696
Study type Interventional
Source University Hospital, Lille
Contact
Status Completed
Phase N/A
Start date June 27, 2018
Completion date November 22, 2022
View Details
See also
  Status Clinical Trial Phase
Completed NCT03299920 - Opioid Consumption After Knee Arthroscopy N/A
Completed NCT04061629 - Minimal Occlusive Pressure With Cuffed ETTs: The Effect of 3 Different Sizes of cETT on Intracuff Pressure in Children
Not yet recruiting NCT03213548 - Aesthetic and Functional Results of Alar Base Modifications in Rhinoplasty N/A
Completed NCT06164158 - Role of Procedural Videos in Teaching the Surgery Residents N/A
Recruiting NCT03854669 - Experimental Pain Reporting Accuracy and Clinical Post-operative Pain N/A
Active, not recruiting NCT03776591 - Open D3 Right Hemicolectomy Compared to Laparoscopic CME for Right Sided Colon Cancer N/A
Completed NCT04332679 - Non-resorbable Membranes Versus Titanium Meshes and Resorbable Membranes N/A
Completed NCT03305666 - Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures Phase 4
Completed NCT05008107 - Virtual Reality as a Perioperative Teaching Tool for Families N/A
Terminated NCT02399111 - A Trial to Evaluate Negative Pressure Incision Management System for Groin Wounds in Vascular Surgery Patients N/A
Terminated NCT00753766 - Multifactorial Pre-operative Intervention in Diabetes Mellitus N/A
Active, not recruiting NCT03684720 - Using 'Guided-Discovery-Learning' to Optimize and Maximize Transfer of Surgical Simulation N/A
Recruiting NCT04134975 - Evaluation of the Contribution of Intraoperative Scans Coupled With the Navigation for the Precision of the Positioning of the Pedicle Screws During a Lumbar Spine Surgery: a Prospective Randomised Study N/A
Completed NCT06148701 - Preoperative Anesthesia Automatic System:a Retrospective Cohort Study
Active, not recruiting NCT04202874 - A Trial Comparing Surgeon-administered TAP Block With Placebo After Midline Laparotomy in Gynecologic Oncology Phase 3
Completed NCT05428579 - Status of Surgical Resection and Histologic Subtype as Predictors of Local Recurrence in Retroperitoneal Liposarcoma
Completed NCT02626546 - Predictors, Risk Factors and Outcome Following Major Surgery
Recruiting NCT06278610 - Pelvic Exenteration and Laterally Extended Pelvic Resection
Recruiting NCT05044832 - Decreasing Emergence Agitation With Personalized Music N/A
Completed NCT04327895 - Surgery in Context of Terrorist Attack : a Survey of French Surgeons