Pulmonary Complication Clinical Trial
Official title:
Multicenter, Randomized, Open Study, Assessing Prophylactic Noninvasive Ventilation in Intensive Care Unit vs Postoperative Standard Care for Patients With High Risk of Postoperative Pulmonary Complication With Preoperative ARISCAT Score
Postoperative pulmonary complications are one of the most common complications after surgery.
Noninvasive ventilation has been proposed post-operatively to prevent postoperative pulmonary
complications.
Prophylactic noninvasive ventilation performed systematically in a non-specific population is
without interest.
The difficulty for the practitioner is to target patients at higher risk of developing a
postoperative pulmonary complications in order to guiding them to a post-operative
specialized care pathway.
The use of the ARISCAT score, validated on a large European prospective cohort, makes it
possible to evaluate, preoperatively, the risk of occurrence of postoperative pulmonary
complication in the patient.
The hypothesis of the present research is that early postoperative preventive treatment with
noninvasive ventilation, in patients at risk of postoperative pulmonary complications
according to the preoperative evaluation according to the ARISCAT score, could have an
interest in reducing these complications with a superior efficiency over standard techniques.
After verification of eligibility criteria and ARISCAT score, patients at high risk of COPD
are randomized in the study.
At the exit of the operating room, patients are referred to the services according to their
randomization arm :
- arm with prophylactic noninvasive ventilation in intensive care unit. Patients will
receive noninvasive ventilation for a maximum of 48 hours. Sessions last 1 hour and are
repeated every 2 to 3 hours
- arm with standard care in conventional care unit. Patients receive standard care such as
physiotherapy.
In both arms, patient follow-up is 7 days maximum.
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