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Surgical Oncology clinical trials

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NCT ID: NCT05953181 Active, not recruiting - Esophageal Cancer Clinical Trials

Statistical Analysis Plan for the SANO-trial: Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Active Surveillance for Oesophageal Cancer

SANO
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

An active surveillance approach is proposed after completion of neoadjuvant chemoradiotherapy (nCRT) for carcinoma of the oesophagus. In this SANO (i.e. Surgery As Needed for Oesophageal cancer) approach, surgical resection is offered only to patients in whom a locoregional regrowth is highly suspected or proven, without distant dissemination. Such an organ-preserving strategy can have great advantages, but is only justified if long-term survival is non-inferior to that of the current standard trimodality approach comprising neoadjuvant chemoradiotherapy followed by standard surgery. The aim of this study is to assess the (cost-)effectiveness (including non-financial costs and survival) of active surveillance for patients with squamous cell- or adenocarcinoma of the oesophagus or oesophago-gastric junction.

NCT ID: NCT05377970 Recruiting - Oncology Clinical Trials

Implementation of a Prehabilitation Program for Surgical Patients

Start date: June 25, 2022
Phase: N/A
Study type: Interventional

Frailty is a state of increased vulnerability to stressors with increased rates of poor outcomes. Surgery is one of these stressors, and previous research has therefore shown increased rates of morbidity and mortality in frail patients undergoing surgery. Prehabilitation programs can help mitigate the negative outcomes associated with frailty. The investigators hope to implement a newly developed prehabilitation pilot program in the Maine Medical Center Surgical Oncology Clinic to initially evaluate adherence, self-efficacy, and health-related quality of life.

NCT ID: NCT04744688 Completed - Clinical trials for Postoperative Complications

Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment

CONTEST
Start date: April 6, 2021
Phase:
Study type: Observational
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NCT ID: NCT03606044 Completed - Kidney Neoplasms Clinical Trials

3D Virtual Models as an Adjunct to Preoperative Surgical Planning

Start date: May 1, 2019
Phase:
Study type: Observational
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NCT ID: NCT03034096 Active, not recruiting - Anesthesia, General Clinical Trials

General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial

GA-CARES
Start date: January 31, 2017
Phase: Phase 4
Study type: Interventional

This is a large pragmatic multicenter trial comparing maintenance of general anesthesia with total intravenous anesthesia using propofol versus volatile agent (sevoflurane, isoflurane, or desflurane) during cancer surgery. The primary endpoint is all-cause mortality.