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Surgical Incision clinical trials

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NCT ID: NCT06202053 Recruiting - Surgical Incision Clinical Trials

An Observational Study on the Quality of Life After Precise Lung Resection Through the Periareolar Incision

Start date: September 28, 2023
Phase:
Study type: Observational [Patient Registry]

With the rapid development of video-assisted thoracoscopic technology, minimally invasive surgery has become the mainstream surgical approach and is widely known to the public. In addition to the pursuit of successful resection, patients seek an improvement in quality of life after surgery, which poses a challenge to surgeons. The surgical quality of uniportal video-assisted thoracoscopic surgery (VATS) is excellent. It has been shown to be superior to conventional VATS in many studies, especially with respect to the length of hospital stay and severity of pain/paresthesia. The rapid increase in the number of patients undergoing uniportal thoracoscopic surgery has led to the gradual widespread use of this technique. Therefore, how to further innovate this technology has become a direction of further research for surgeons. Here, we describe a rare uniportal thoracoscopic procedure through the perirareolar incision that has certain advantages over other uniportal thoracoscopic procedures.

NCT ID: NCT05989386 Recruiting - Clinical trials for Surgical Site Infection

Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

Start date: April 29, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: - Incidence of SSI after intervention - Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.

NCT ID: NCT05897723 Recruiting - Surgical Incision Clinical Trials

Fractional Radiofrequency for Reduction of Surgical Scar Formation

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Safety and Efficacy of Fractional Radiofrequency for the Reduction of Surgical Scar Formation

NCT ID: NCT05702827 Recruiting - Clinical trials for Stress Urinary Incontinence

Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery

Start date: January 23, 2023
Phase: Phase 3
Study type: Interventional

This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.

NCT ID: NCT05618912 Recruiting - Clinical trials for Patient Satisfaction

Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment

Start date: October 17, 2022
Phase: N/A
Study type: Interventional

Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which will be left in place for 7 days(Experimental) or the standard dressing (Control) that will be covered with petrolatum jelly and bandaging during this time period, which has to be re-applied daily. Patients and dermatologic surgeons will then complete surveys 7 days, 30 days, and 90 days after surgery to evaluate the cosmetic appearance of these scars.

NCT ID: NCT04350697 Recruiting - Surgery Clinical Trials

Mini-invasive Approaches to Aortic Surgery

MSvsMT
Start date: January 1, 1999
Phase:
Study type: Observational

There are many different types of mini-invasive approaches to aortic surgery. Ministernotomy and anterior right minithoracotomy are the two main techniques applied for minimally invasive aortic valve replacement, but if one of them is superior in terms of patient outcomes it is not still clear. Therefore, the aim of this study is to compare the immediate and long-term outcomes of these two techniques.

NCT ID: NCT04164953 Recruiting - Surgical Incision Clinical Trials

Tolerance and Efficacy Study of Second-line Surgery After Percutaneous Needle Aponeurotomy for Dupuytren's Disease.

URAM3
Start date: April 12, 2019
Phase: N/A
Study type: Interventional

As part of a graduated medical-surgical strategy, and in our practice, surgery for Dupuytren's disease appears as a second-line treatment indicated in a situation of failure after treatment with percutaneous needle aponeurotomy.The results of second-line surgery in terms of safety and efficacy have not been specifically evaluated in patients who underwent failed percutaneous needle aponeurotomy. This evaluation nevertheless appears necessary for the validation of a medical-surgical strategy during Dupuytren's disease.

NCT ID: NCT03561376 Recruiting - Clinical trials for Surgical Site Infection

Zinc Oxide Versus Petrolatum Following Skin Surgery

Start date: September 1, 2021
Phase: Early Phase 1
Study type: Interventional

Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than or equal to 4.5cm in length will be invited to participate in this split scar, head to head study comparing zinc oxide and petrolatum. Patients will apply respective ointments to each half of scar daily for one month and maintain a log of these activities. They will be seen at 1 week, 4 weeks, 8 weeks, and 6 months post-operatively for photographic scar assessment and to complete the patient portion of the Patient and Observer Scar Assessment Scale (POSAS), a quantitative objective assessment of scar appearance. Trained observers (board-certified dermatologists) will score the observer portion of the scale. POSAS outcomes, post-operative infections, linear density of epidermal seal will be assessed at the 1 week, 4 weeks, 8 weeks, and 6 months post-operative periods and compared between the two groups. Participants will have parking validated for all visits and upon completion of all portions of the study will receive a standardized skin care gift bag containing samples for hypoallergenic skin care products (washes, moisturizers, etc.).

NCT ID: NCT02992951 Recruiting - Wound Infection Clinical Trials

DACC in the REduction of Surgical Site INfection

DRESSINg
Start date: January 19, 2017
Phase: N/A
Study type: Interventional

Surgical site infection is an infection at a place in the body where surgery has taken place, and has been reported in around 5% of people undergoing an operation. In vascular surgery, infection rates are as high as 30%. Methods to reduce this rate of infection should be investigated thoroughly for their effectiveness and cost-effectiveness. The investigators aim to conduct a research trial examining one such method. Leukomed Sorbact is a wound dressing coated with a chemical (DACC) derived from spider-silk that interacts with, and binds bacteria, causing them to be mechanically removed from a wound when the dressing is changed. The trial aims to compare the effectiveness of this dressing to a standard, non-coated dressing, in the reduction of surgical site infection. 718 patients from a number of centres across the UK will be recruited to this study. Adult patients who are having a vascular surgery operation will be approached for entry into the trial. The trial will be explained to them, as well as an explanation that participation is voluntary and their operation or other aspects of their care will not be impacted in any way should participants not wish to participate. Participants will be randomised by computer into one of two groups - one group whose wounds are dressed with Leukomed Sorbact, and the other whose wounds are dressed with a standard dressing. Patients will be followed up at 30 days post-operatively. At the follow up, their wounds will be inspected for infection, and participants will be asked to complete short questionnaires measuring quality of life. Quality of life will also be assessed at 3 months post surgery. The trial will aim to answer a number of questions, with the primary question being does a DACC coated dressing applied after an operation reduce the risk of an infection at the surgery site? It will also ask whether this treatment is cost-effective and whether it promotes satisfactory healing and evaluate the overall carbon footprint impact of each intervention. Studies Within a Trial will be conducted to validate a remote diagnostic measure for detecting surgical site infection using wound images and the Bluebelle Wound Healing Questionnaire, evaluate feasibility of novel hair removal methods such as epilation and waxing, carbon footprint modelling within randomised controlled trials.

NCT ID: NCT02989363 Recruiting - Surgical Incision Clinical Trials

Evaluation of the Use of Resources and Costs

Start date: October 2011
Phase: N/A
Study type: Interventional

Evaluation of the use of resources and costs with O-arm in deep brain stimulation (DBS) surgeries and complex back surgeries