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Alleviating Effects Against Dry Eye by Oral Intake of Cordyceps Cicadae Mycelia

Dry Eye Clinical Trial

Official title:
Alleviating Effects Against Dry Eye by Oral Intake of Cordyceps Cicadae Mycelia

Clinical Trial Summary

Cordyceps cicadae mycelia was tested for amelioration of dry eye symptoms through dietary supplementation. Its efficacy in relief of human dry eye status was assessed by randomized, double-blinded tests, including multiple assessments. The results were compared between the placebo group and the experimental group.

Clinical Trial Description

Former animal studies had shown that Cordyceps cicadae mycelia can effectively ameliorate UVB-induced dry eye symptoms. This study further investigated its efficacy in human dry eye status by randomized, double-blinded tests, including dry eye questionnaires, blood tests, salivary tests, tear volume test, intra-ocular pressure assessments, ocular surface photography, corneal fluorescein stain, tear film breakup time test, fundus photography, and cornea impression cytology. All tests were performed again after 3 months of dietary supplement of either samples or placebo. A total of 97 participants completed the trial. The data were analyzed by paired-t test and compared between the placebo and the experimental groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04063735
Study type Interventional
Source Chung Shan Medical University
Contact
Status Completed
Phase N/A
Start date December 1, 2016
Completion date November 30, 2017
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