Substance Use Clinical Trial
Official title:
Using Re-inforcement Learning to Automatically Adapt a Remote Therapy Intervention (RTI) for Reducing Adolescent Violence Involvement
This study will use a randomized control trial (RCT) design to administer two versions of a multisession remote behavioral intervention for youth seeking Emergency Department care for a violent injury with the goal to reduce their violence involvement and associated negative behaviors and consequences. The study examines two versions of the remote therapy intervention - a standard RTI (S-RTI) and an Artificial Intelligence RTI (AI-RTI). The application of a just-in-time adaptive strategy to address youth violence is an important and novel direction for this research, particularly given the need to understand best practices for delivering behavioral interventions among lower-income populations.
The Specific Aims for the proposed study are to refine the Remote Therapy Intervention (RTI) for delivery using a standardized remote therapy package (S-RTI; 1 ED + 5 remote sessions) based on a piloted RTI and an adaptive RTI that optimizes bi-weekly dose and intervention intensity between four levels of therapy (remote therapy+, remote therapy; automated electronic tailored therapy; none) based on a reinforcement learning (RL) algorithm [AI-RTI]. A total of 750 youth (age=14-24) seeking ED care for a violent injury will be enrolled and randomly assigned (stratified by age/gender) to the S-RTI (n=250), AI-RTI (n=300), and a control (EUC; n=200) condition. In addition to the randomized assignment, all youth will take a daily assessment over the course of the intervention timeline. Outcomes will be assessed at 6 and 12 months. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT05806840 -
Rapid Adaptation to Prevent Drug Use
|
N/A | |
Recruiting |
NCT06003725 -
Cultural Adaptation of Drug Treatment for DJJ Youth
|
N/A | |
Recruiting |
NCT05414344 -
A Brief Intervention for Alcohol Users With Interpersonal Trauma
|
N/A | |
Recruiting |
NCT05768815 -
Optimizing Mental Health for Infants Exposed to Early Adversity: A Comparison of Breaking the Cycle and Maxxine Wright
|
N/A | |
Completed |
NCT05606601 -
An Online Intervention Addressing Mental Health and Substance Use in University Students
|
N/A | |
Completed |
NCT03489434 -
Technology-Based Prevention for Adolescents in Primary Care
|
N/A | |
Completed |
NCT04284813 -
Families With Substance Use and Psychosis: A Pilot Study
|
N/A | |
Recruiting |
NCT05899101 -
The Impact of Opioid and Cannabis Exposure on Fetal Growth
|
||
Completed |
NCT02990026 -
Specialty Mental Health Probation in North Carolina
|
N/A | |
Not yet recruiting |
NCT06116266 -
Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)
|
N/A | |
Not yet recruiting |
NCT03249428 -
E-Cigarette Inner City RCT
|
N/A | |
Active, not recruiting |
NCT03129334 -
Preventing Prescription Drug Abuse in Middle School Students
|
N/A | |
Completed |
NCT04183400 -
Safety Awareness For Empowerment (SAFE): An RCT With Young People Experiencing Homelessness
|
N/A | |
Completed |
NCT02112201 -
The ProGirls Study
|
N/A | |
Completed |
NCT01752998 -
Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings
|
N/A | |
Terminated |
NCT01661517 -
Brief Intervention and Referral to Treatment With Substance Use Disorders in the Emergency Room Setting
|
Phase 0 | |
Completed |
NCT01351454 -
Behavioral Depression Treatment for African American HIV-infected Substance Users
|
N/A | |
Completed |
NCT01511380 -
Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth
|
Phase 2 | |
Completed |
NCT01154309 -
Group CBT for Depression and AOD Disorders
|
Phase 1 | |
Completed |
NCT00996541 -
Support To Reunite Involve and Value Each Other
|
N/A |