Clinical Trials Logo

Clinical Trial Details — Status: Active, not recruiting

Administrative data

NCT number NCT01621711
Other study ID # 10-01606
Secondary ID
Status Active, not recruiting
Phase N/A
First received
Last updated
Start date March 2011
Est. completion date December 31, 2025

Study information

Verified date May 2024
Source Kaiser Permanente
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This component of a larger Center of Research Excellence Grant improves treatment for drug abuse by developing effective linkages between specialty drug treatment and primary health care.


Description:

This is a longitudinal two-arm quasi-experimental 3-month alternating off/on design over a 30 month period in which, after a random start, the Linkage condition alternately is added to Usual Care in the Chemical Dependency (CD) clinic and then removed. We compare Usual Care to Usual Care plus Linkage. Follow-up interviews will be conducted at 6, 12 and 24 months. The Linkage intervention includes Usual Care plus 1) sessions on activation regarding overall health behaviors and on selecting a Primary Care physician and communicating with him/her, and 2) a linkage phone call (and/or a facilitated email) with the patient, clinician, and Primary Care physician. The intervention aims to place drug abuse problems in the context of overall health and health care and to activate patients to increase involvement in their own health care.


Recruitment information / eligibility

Status Active, not recruiting
Enrollment 504
Est. completion date December 31, 2025
Est. primary completion date December 31, 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Research participants will be adult patients at the Kaiser Permanente San Francisco Chemical Dependency Recovery Program, who have completed 2 weeks of treatment. Exclusion Criteria: - Patients with a diagnosis of dementia, mental retardation, or who are actively psychotic or suicidal will be excluded by their clinician.

Study Design


Intervention

Behavioral:
Linkage patient activation intervention
Usual Care plus Linkage encompassed Usual Care with the exception that the six 45-min Linkage patient activation education groups replaced the six 45-min Usual Care medical education groups, plus a linkage phone call (and/or a facilitated email) with the patient, clinician, and Primary Care physician. The patient activation intervention components -- 1) six 45-min Linkage sessions on activation regarding overall health behaviors and 2) a linkage phone call (and/or a facilitated email) with the patient, clinician, and PC physician -- were delivered by a clinical psychologist.

Locations

Country Name City State
United States Kaiser Permanente, Chemical Dependency Recovery Program San Francisco California

Sponsors (2)

Lead Sponsor Collaborator
Kaiser Permanente Kaiser Foundation Research Institute

Country where clinical trial is conducted

United States, 

References & Publications (111)

Anglin MD, Hser YI, Booth MW. Sex differences in addict careers. 4. Treatment. Am J Drug Alcohol Abuse. 1987;13(3):253-80. doi: 10.3109/00952998709001513. — View Citation

Bobo JK, Davis CM. Recovering staff and smoking in chemical dependency programs in rural Nebraska. J Subst Abuse Treat. 1993 Mar-Apr;10(2):221-7. doi: 10.1016/0740-5472(93)90047-6. — View Citation

Bobo JK, Lando HA, Walker RD, McIlvain HE. Predictors of tobacco quit attempts among recovering alcoholics. J Subst Abuse. 1996;8(4):431-43. doi: 10.1016/s0899-3289(96)90004-8. — View Citation

Bodenheimer T, Wagner EH, Grumbach K. Improving primary care for patients with chronic illness. JAMA. 2002 Oct 9;288(14):1775-9. doi: 10.1001/jama.288.14.1775. — View Citation

Bodenheimer T, Wagner EH, Grumbach K. Improving primary care for patients with chronic illness: the chronic care model, Part 2. JAMA. 2002 Oct 16;288(15):1909-14. doi: 10.1001/jama.288.15.1909. — View Citation

Booth BM, Blow FC, Cook CA, Bunn JY, Fortney JC. Relationship between inpatient alcoholism treatment and longitudinal changes in health care utilization. J Stud Alcohol. 1997 Nov;58(6):625-37. doi: 10.15288/jsa.1997.58.625. — View Citation

Booth BM, McLaughlin YS. Barriers to and need for alcohol services for women in rural populations. Alcohol Clin Exp Res. 2000 Aug;24(8):1267-75. — View Citation

Booth BM, Yates WR, Petty F, Brown K. Patient factors predicting early alcohol-related readmissions for alcoholics: role of alcoholism severity and psychiatric co-morbidity. J Stud Alcohol. 1991 Jan;52(1):37-43. doi: 10.15288/jsa.1991.52.37. — View Citation

Brennan PL, Kagay CR, Geppert JJ, Moos RH. Elderly Medicare inpatients with substance use disorders: characteristics and predictors of hospital readmissions over a four-year interval. J Stud Alcohol. 2000 Nov;61(6):891-5. doi: 10.15288/jsa.2000.61.891. — View Citation

Chou SP, Grant BF, Dawson DA. Medical consequences of alcohol consumption--United States, 1992. Alcohol Clin Exp Res. 1996 Nov;20(8):1423-9. doi: 10.1111/j.1530-0277.1996.tb01144.x. — View Citation

Clayton RR. Multiple drug use. Epidemiology, correlates, and consequences. Recent Dev Alcohol. 1986;4:7-38. — View Citation

Compton WM, Thomas YF, Stinson FS, Grant BF. Prevalence, correlates, disability, and comorbidity of DSM-IV drug abuse and dependence in the United States: results from the national epidemiologic survey on alcohol and related conditions. Arch Gen Psychiatry. 2007 May;64(5):566-76. doi: 10.1001/archpsyc.64.5.566. — View Citation

Cooper LA, Gonzales JJ, Gallo JJ, Rost KM, Meredith LS, Rubenstein LV, Wang NY, Ford DE. The acceptability of treatment for depression among African-American, Hispanic, and white primary care patients. Med Care. 2003 Apr;41(4):479-89. doi: 10.1097/01.MLR.0000053228.58042.E4. — View Citation

Cooper-Patrick L, Gallo JJ, Powe NR, Steinwachs DM, Eaton WW, Ford DE. Mental health service utilization by African Americans and Whites: the Baltimore Epidemiologic Catchment Area Follow-Up. Med Care. 1999 Oct;37(10):1034-45. doi: 10.1097/00005650-199910000-00007. — View Citation

Dawson DA, Grant BF. Gender effects in diagnosing alcohol abuse and dependence. J Clin Psychol. 1993 Mar;49(2):298-307. doi: 10.1002/1097-4679(199303)49:23.0.co;2-z. — View Citation

Dennis M, Scott CK. Managing addiction as a chronic condition. Addict Sci Clin Pract. 2007 Dec;4(1):45-55. doi: 10.1151/ascp074145. — View Citation

Dennis ML, Scott CK, Funk R, Foss MA. The duration and correlates of addiction and treatment careers. J Subst Abuse Treat. 2005;28 Suppl 1:S51-62. doi: 10.1016/j.jsat.2004.10.013. — View Citation

Fleming MF, Graham AW. Screening and brief interventions for alcohol use disorders in managed care settings. Recent Dev Alcohol. 2001;15:393-416. doi: 10.1007/978-0-306-47193-3_22. — View Citation

Fleming MF, Mundt MP, French MT, Manwell LB, Stauffacher EA, Barry KL. Benefit-cost analysis of brief physician advice with problem drinkers in primary care settings. Med Care. 2000 Jan;38(1):7-18. doi: 10.1097/00005650-200001000-00003. — View Citation

Fleming MF, Mundt MP, French MT, Manwell LB, Stauffacher EA, Barry KL. Brief physician advice for problem drinkers: long-term efficacy and benefit-cost analysis. Alcohol Clin Exp Res. 2002 Jan;26(1):36-43. — View Citation

Friedmann PD, Hendrickson JC, Gerstein DR, Zhang Z, Stein MD. Do mechanisms that link addiction treatment patients to primary care influence subsequent utilization of emergency and hospital care? Med Care. 2006 Jan;44(1):8-15. doi: 10.1097/01.mlr.0000188913.50489.77. — View Citation

Friedmann PD, Jiang L, Richter KP. Cigarette smoking cessation services in outpatient substance abuse treatment programs in the United States. J Subst Abuse Treat. 2008 Mar;34(2):165-72. doi: 10.1016/j.jsat.2007.02.006. Epub 2007 May 23. — View Citation

Friedmann PD, Saitz R, Samet JH. Management of adults recovering from alcohol or other drug problems: relapse prevention in primary care. JAMA. 1998 Apr 15;279(15):1227-31. doi: 10.1001/jama.279.15.1227. — View Citation

Friedmann PD, Zhang Z, Hendrickson J, Stein MD, Gerstein DR. Effect of primary medical care on addiction and medical severity in substance abuse treatment programs. J Gen Intern Med. 2003 Jan;18(1):1-8. doi: 10.1046/j.1525-1497.2003.10601.x. — View Citation

Fuller BE, Guydish J, Tsoh J, Reid MS, Resnick M, Zammarelli L, Ziedonis DM, Sears C, McCarty D. Attitudes toward the integration of smoking cessation treatment into drug abuse clinics. J Subst Abuse Treat. 2007 Jan;32(1):53-60. doi: 10.1016/j.jsat.2006.06.011. Epub 2006 Sep 26. — View Citation

Gfroerer J, Penne M, Pemberton M, Folsom R. Substance abuse treatment need among older adults in 2020: the impact of the aging baby-boom cohort. Drug Alcohol Depend. 2003 Mar 1;69(2):127-35. doi: 10.1016/s0376-8716(02)00307-1. — View Citation

Godley MD, Godley SH, Dennis ML, Funk R, Passetti LL. Preliminary outcomes from the assertive continuing care experiment for adolescents discharged from residential treatment. J Subst Abuse Treat. 2002 Jul;23(1):21-32. doi: 10.1016/s0740-5472(02)00230-1. — View Citation

Godley MD, Godley SH, Dennis ML, Funk RR, Passetti LL. The effect of assertive continuing care on continuing care linkage, adherence and abstinence following residential treatment for adolescents with substance use disorders. Addiction. 2007 Jan;102(1):81-93. doi: 10.1111/j.1360-0443.2006.01648.x. — View Citation

Godley SH, Godley MD, Wright KL, Funk RR, Petry NM. Contingent reinforcement of personal goal activities for adolescents with substance use disorders during post-residential continuing care. Am J Addict. 2008 Jul-Aug;17(4):278-86. doi: 10.1080/10550490802138798. — View Citation

Gonzales JJ, Insel TR. The conundrum of co-occurring mental and substance use disorders: opportunities for research. Biol Psychiatry. 2004 Nov 15;56(10):723-5. doi: 10.1016/j.biopsych.2004.09.007. No abstract available. — View Citation

Gordon AJ, Fiellin DA, Friedmann PD, Gourevitch MN, Kraemer KL, Arnsten JH, Saitz R; Society of General Internal Medicine's Substance Abuse Interest Group. Update in addiction medicine for the primary care clinician. J Gen Intern Med. 2008 Dec;23(12):2112-6. doi: 10.1007/s11606-008-0806-7. Epub 2008 Oct 2. No abstract available. — View Citation

Gordon AJ, Sullivan LE, Alford DP, Arnsten JH, Gourevitch MN, Kertesz SG, Kunins HV, Merrill JO, Samet JH, Fiellin DA. Update in addiction medicine for the generalist. J Gen Intern Med. 2007 Aug;22(8):1190-4. doi: 10.1007/s11606-007-0133-4. Epub 2007 May 10. No abstract available. — View Citation

Grella CE, Greenwell L. Treatment needs and completion of community-based aftercare among substance-abusing women offenders. Womens Health Issues. 2007 Jul-Aug;17(4):244-55. doi: 10.1016/j.whi.2006.11.005. Epub 2007 Jun 4. — View Citation

Hassan I, McCabe R, Priebe S. Professional-patient communication in the treatment of mental illness: a review. Commun Med. 2007;4(2):141-52. doi: 10.1515/CAM.2007.018. — View Citation

Hibbard JH, Stockard J, Mahoney ER, Tusler M. Development of the Patient Activation Measure (PAM): conceptualizing and measuring activation in patients and consumers. Health Serv Res. 2004 Aug;39(4 Pt 1):1005-26. doi: 10.1111/j.1475-6773.2004.00269.x. — View Citation

Holder HD, Blose JO. The reduction of health care costs associated with alcoholism treatment: a 14-year longitudinal study. J Stud Alcohol. 1992 Jul;53(4):293-302. doi: 10.15288/jsa.1992.53.293. — View Citation

Holman H, Lorig K. Patients as partners in managing chronic disease. Partnership is a prerequisite for effective and efficient health care. BMJ. 2000 Feb 26;320(7234):526-7. doi: 10.1136/bmj.320.7234.526. No abstract available. — View Citation

Hser YI, Anglin MD, Booth MW. Sex differences in addict careers. 3. Addiction. Am J Drug Alcohol Abuse. 1987;13(3):231-51. doi: 10.3109/00952998709001512. — View Citation

Hser YI, Anglin MD, Grella C, Longshore D, Prendergast ML. Drug treatment careers. A conceptual framework and existing research findings. J Subst Abuse Treat. 1997 Nov-Dec;14(6):543-58. doi: 10.1016/s0740-5472(97)00016-0. — View Citation

Hser YI, Anglin MD, McGlothlin W. Sex differences in addict careers. 1. Initiation of use. Am J Drug Alcohol Abuse. 1987;13(1-2):33-57. doi: 10.3109/00952998709001499. — View Citation

Hser YI, McCarthy WJ, Anglin MD. Tobacco use as a distal predictor of mortality among long-term narcotics addicts. Prev Med. 1994 Jan;23(1):61-9. doi: 10.1006/pmed.1994.1009. — View Citation

Hubbard RL. Treating combined alcohol and drug abuse in community-based programs. Recent Dev Alcohol. 1990;8:273-83. — View Citation

Hurt RD, Offord KP, Croghan IT, Gomez-Dahl L, Kottke TE, Morse RM, Melton LJ 3rd. Mortality following inpatient addictions treatment. Role of tobacco use in a community-based cohort. JAMA. 1996 Apr 10;275(14):1097-103. doi: 10.1001/jama.275.14.1097. Erratum In: JAMA 1996 Sep 11;276(10):784. — View Citation

Hurt RD, Patten CA. Treatment of tobacco dependence in alcoholics. Recent Dev Alcohol. 2003;16:335-59. doi: 10.1007/0-306-47939-7_23. — View Citation

Jerrell JM, Wieduwilt KM, Macey DV. Use and costs of public-sector behavioral health services for african-american and white women. Psychiatr Serv. 2002 Feb;53(2):195-200. doi: 10.1176/appi.ps.53.2.195. — View Citation

Johnson RL, Roter D, Powe NR, Cooper LA. Patient race/ethnicity and quality of patient-physician communication during medical visits. Am J Public Health. 2004 Dec;94(12):2084-90. doi: 10.2105/ajph.94.12.2084. — View Citation

Kalman D. Smoking cessation treatment for substance misusers in early recovery: a review of the literature and recommendations for practice. Subst Use Misuse. 1998 Aug;33(10):2021-47. doi: 10.3109/10826089809069815. — View Citation

Kania J, Kofoed L. Drug use by alcoholics in outpatient treatment. Am J Drug Alcohol Abuse. 1984;10(4):529-34. doi: 10.3109/00952998409001490. — View Citation

Kaplan SH, Gandek B, Greenfield S, Rogers W, Ware JE. Patient and visit characteristics related to physicians' participatory decision-making style. Results from the Medical Outcomes Study. Med Care. 1995 Dec;33(12):1176-87. doi: 10.1097/00005650-199512000-00002. — View Citation

Kashner TM, Rodell DE, Ogden SR, Guggenheim FG, Karson CN. Outcomes and costs of two VA inpatient treatment programs for older alcoholic patients. Hosp Community Psychiatry. 1992 Oct;43(10):985-9. doi: 10.1176/ps.43.10.985. — View Citation

Lemke S, Moos RH. Prognosis of older patients in mixed-age alcoholism treatment programs. J Subst Abuse Treat. 2002 Jan;22(1):33-43. doi: 10.1016/s0740-5472(01)00209-4. — View Citation

Liberto JG, Oslin DW, Ruskin PE. Alcoholism in older persons: a review of the literature. Hosp Community Psychiatry. 1992 Oct;43(10):975-84. doi: 10.1176/ps.43.10.975. — View Citation

Lorig KR, Holman H. Self-management education: history, definition, outcomes, and mechanisms. Ann Behav Med. 2003 Aug;26(1):1-7. doi: 10.1207/S15324796ABM2601_01. — View Citation

Marsh JC, Cao D, D'Aunno T. Gender differences in the impact of comprehensive services in substance abuse treatment. J Subst Abuse Treat. 2004 Dec;27(4):289-300. doi: 10.1016/j.jsat.2004.08.004. — View Citation

McKay JR, Carise D, Dennis ML, Dupont R, Humphreys K, Kemp J, Reynolds D, White W, Armstrong R, Chalk M, Haberle B, McLellan T, O'Connor G, Pakull B, Schwartzlose J. Extending the benefits of addiction treatment: practical strategies for continuing care and recovery. J Subst Abuse Treat. 2009 Mar;36(2):127-30. doi: 10.1016/j.jsat.2008.10.005. No abstract available. — View Citation

McKay JR, Carise D. State of the science: Extending the benefits of addiction treatment. J Subst Abuse Treat. 2009 Mar;36(2):172-3. doi: 10.1016/j.jsat.2008.10.007. No abstract available. — View Citation

McKay JR, Lynch KG, Shepard DS, Pettinati HM. The effectiveness of telephone-based continuing care for alcohol and cocaine dependence: 24-month outcomes. Arch Gen Psychiatry. 2005 Feb;62(2):199-207. doi: 10.1001/archpsyc.62.2.199. — View Citation

McKay JR. Continuing care research: what we have learned and where we are going. J Subst Abuse Treat. 2009 Mar;36(2):131-45. doi: 10.1016/j.jsat.2008.10.004. — View Citation

McKay JR. Is there a case for extended interventions for alcohol and drug use disorders? Addiction. 2005 Nov;100(11):1594-610. doi: 10.1111/j.1360-0443.2005.01208.x. — View Citation

McLellan AT, Alterman AI, Metzger DS, Grissom GR, Woody GE, Luborsky L, O'Brien CP. Similarity of outcome predictors across opiate, cocaine, and alcohol treatments: role of treatment services. J Consult Clin Psychol. 1994 Dec;62(6):1141-58. doi: 10.1037//0022-006x.62.6.1141. — View Citation

Mendelson DN, Schwartz WB. The effects of aging and population growth on health care costs. Health Aff (Millwood). 1993 Spring;12(1):119-25. doi: 10.1377/hlthaff.12.1.119. — View Citation

Mertens JR, Flisher AJ, Satre DD, Weisner CM. The role of medical conditions and primary care services in 5-year substance use outcomes among chemical dependency treatment patients. Drug Alcohol Depend. 2008 Nov 1;98(1-2):45-53. doi: 10.1016/j.drugalcdep.2008.04.007. Epub 2008 Jun 20. — View Citation

Mertens JR, Lu YW, Parthasarathy S, Moore C, Weisner CM. Medical and psychiatric conditions of alcohol and drug treatment patients in an HMO: comparison with matched controls. Arch Intern Med. 2003 Nov 10;163(20):2511-7. doi: 10.1001/archinte.163.20.2511. — View Citation

Mertens JR, Weisner CM. Predictors of substance abuse treatment retention among women and men in an HMO. Alcohol Clin Exp Res. 2000 Oct;24(10):1525-33. — View Citation

Montoya ID. Infectious diseases and anemia in a sample of out-of-treatment drug users. Am J Manag Care. 1998 Sep;4(9):1257-64. — View Citation

Moos RH, Brennan PL, Mertens JR. Diagnostic subgroups and predictors of one-year re-admission among late-middle-aged and older substance abuse patients. J Stud Alcohol. 1994 Mar;55(2):173-83. doi: 10.15288/jsa.1994.55.173. — View Citation

Moos RH, Mertens JR, Brennan PL. Patterns of diagnosis and treatment among late-middle-aged and older substance abuse patients. J Stud Alcohol. 1993 Jul;54(4):479-87. doi: 10.15288/jsa.1993.54.479. — View Citation

Moos RH, Mertens JR, Brennan PL. Rates and predictors of four-year readmission among late-middle-aged and older substance abuse patients. J Stud Alcohol. 1994 Sep;55(5):561-70. doi: 10.15288/jsa.1994.55.561. — View Citation

Mosen DM, Schmittdiel J, Hibbard J, Sobel D, Remmers C, Bellows J. Is patient activation associated with outcomes of care for adults with chronic conditions? J Ambul Care Manage. 2007 Jan-Mar;30(1):21-9. doi: 10.1097/00004479-200701000-00005. — View Citation

Myers MG, MacPherson L. Smoking cessation efforts among substance abusing adolescents. Drug Alcohol Depend. 2004 Feb 7;73(2):209-13. doi: 10.1016/j.drugalcdep.2003.09.008. — View Citation

Nease RF Jr, Brooks WB. Patient desire for information and decision making in health care decisions: the Autonomy Preference Index and the Health Opinion Survey. J Gen Intern Med. 1995 Nov;10(11):593-600. doi: 10.1007/BF02602742. — View Citation

Ornstein P, Cherepon JA. Demographic variables as predictors of alcoholism treatment outcome. J Stud Alcohol. 1985 Sep;46(5):425-32. doi: 10.15288/jsa.1985.46.425. — View Citation

Oslin DW, Pettinati H, Volpicelli JR. Alcoholism treatment adherence: older age predicts better adherence and drinking outcomes. Am J Geriatr Psychiatry. 2002 Nov-Dec;10(6):740-7. — View Citation

Oslin DW. Alcohol use in late life: disability and comorbidity. J Geriatr Psychiatry Neurol. 2000 Fall;13(3):134-40. doi: 10.1177/089198870001300307. — View Citation

Parthasarathy S, Weisner CM. Five-year trajectories of health care utilization and cost in a drug and alcohol treatment sample. Drug Alcohol Depend. 2005 Nov 1;80(2):231-40. doi: 10.1016/j.drugalcdep.2005.04.004. — View Citation

Phibbs CS, Swindle RW, Recine B. Does case mix matter for substance abuse treatment? A comparison of observed and case mix-adjusted readmission rates for inpatient substance abuse treatment in the Department of Veterans Affairs. Health Serv Res. 1997 Feb;31(6):755-71. — View Citation

Polder JJ, Bonneux L, Meerding WJ, van der Maas PJ. Age-specific increases in health care costs. Eur J Public Health. 2002 Mar;12(1):57-62. doi: 10.1093/eurpub/12.1.57. — View Citation

Redelmeier DA, Tan SH, Booth GL. The treatment of unrelated disorders in patients with chronic medical diseases. N Engl J Med. 1998 May 21;338(21):1516-20. doi: 10.1056/NEJM199805213382106. — View Citation

Rice C, Longabaugh R, Beattie M, Noel N. Age group differences in response to treatment for problematic alcohol use. Addiction. 1993 Oct;88(10):1369-75. doi: 10.1111/j.1360-0443.1993.tb02023.x. — View Citation

Richter KP, Ahluwalia HK, Mosier MC, Nazir N, Ahluwalia JS. A population-based study of cigarette smoking among illicit drug users in the United States. Addiction. 2002 Jul;97(7):861-9. doi: 10.1046/j.1360-0443.2002.00162.x. — View Citation

Ritsher JB, McKellar JD, Finney JW, Otilingam PG, Moos RH. Psychiatric comorbidity, continuing care and mutual help as predictors of five-year remission from substance use disorders. J Stud Alcohol. 2002 Nov;63(6):709-15. doi: 10.15288/jsa.2002.63.709. — View Citation

Roman PM. Biological features of women's alcohol use: a review. Public Health Rep. 1988 Nov-Dec;103(6):628-37. — View Citation

Saitz R, Horton NJ, Larson MJ, Winter M, Samet JH. Primary medical care and reductions in addiction severity: a prospective cohort study. Addiction. 2005 Jan;100(1):70-8. doi: 10.1111/j.1360-0443.2005.00916.x. — View Citation

Saitz R, Larson MJ, Horton NJ, Winter M, Samet JH. Linkage with primary medical care in a prospective cohort of adults with addictions in inpatient detoxification: room for improvement. Health Serv Res. 2004 Jun;39(3):587-606. doi: 10.1111/j.1475-6773.2004.00246.x. — View Citation

Samet JH, Friedmann P, Saitz R. Benefits of linking primary medical care and substance abuse services: patient, provider, and societal perspectives. Arch Intern Med. 2001 Jan 8;161(1):85-91. doi: 10.1001/archinte.161.1.85. — View Citation

Samet JH, Larson MJ, Horton NJ, Doyle K, Winter M, Saitz R. Linking alcohol- and drug-dependent adults to primary medical care: a randomized controlled trial of a multi-disciplinary health intervention in a detoxification unit. Addiction. 2003 Apr;98(4):509-16. doi: 10.1046/j.1360-0443.2003.00328.x. — View Citation

Satre DD, Gordon NP, Weisner C. Alcohol consumption, medical conditions, and health behavior in older adults. Am J Health Behav. 2007 May-Jun;31(3):238-48. doi: 10.5555/ajhb.2007.31.3.238. — View Citation

Satre DD, Mertens J, Arean PA, Weisner C. Contrasting outcomes of older versus middle-aged and younger adult chemical dependency patients in a managed care program. J Stud Alcohol. 2003 Jul;64(4):520-30. doi: 10.15288/jsa.2003.64.520. — View Citation

Satre DD, Mertens JR, Arean PA, Weisner C. Five-year alcohol and drug treatment outcomes of older adults versus middle-aged and younger adults in a managed care program. Addiction. 2004 Oct;99(10):1286-97. doi: 10.1111/j.1360-0443.2004.00831.x. — View Citation

Schmittdiel J, Mosen DM, Glasgow RE, Hibbard J, Remmers C, Bellows J. Patient Assessment of Chronic Illness Care (PACIC) and improved patient-centered outcomes for chronic conditions. J Gen Intern Med. 2008 Jan;23(1):77-80. doi: 10.1007/s11606-007-0452-5. Epub 2007 Nov 21. — View Citation

Schuckit MA, Smith TL. An 8-year follow-up of 450 sons of alcoholic and control subjects. Arch Gen Psychiatry. 1996 Mar;53(3):202-10. doi: 10.1001/archpsyc.1996.01830030020005. — View Citation

Sellers EM, Ciraulo DA, DuPont RL, Griffiths RR, Kosten TR, Romach MK, Woody GE. Alprazolam and benzodiazepine dependence. J Clin Psychiatry. 1993 Oct;54 Suppl:64-75; discussion 76-7. — View Citation

Seshamani M, Gray A. Health care expenditures and ageing: an international comparison. Appl Health Econ Health Policy. 2003;2(1):9-16. — View Citation

Skog OJ, Duckert F. The development of alcoholics' and heavy drinkers' consumption: a longitudinal study. J Stud Alcohol. 1993 Mar;54(2):178-88. doi: 10.15288/jsa.1993.54.178. — View Citation

Stein MD. Medical consequences of substance abuse. Psychiatr Clin North Am. 1999 Jun;22(2):351-70. doi: 10.1016/s0193-953x(05)70081-2. — View Citation

Sterling S, Chi F, Campbell C, Weisner C. Three-year chemical dependency and mental health treatment outcomes among adolescents: the role of continuing care. Alcohol Clin Exp Res. 2009 Aug;33(8):1417-29. doi: 10.1111/j.1530-0277.2009.00972.x. Epub 2009 Apr 30. — View Citation

Street RL Jr, Gordon HS, Ward MM, Krupat E, Kravitz RL. Patient participation in medical consultations: why some patients are more involved than others. Med Care. 2005 Oct;43(10):960-9. doi: 10.1097/01.mlr.0000178172.40344.70. — View Citation

Street RL Jr. Gender differences in health care provider-patient communication: are they due to style, stereotypes, or accommodation? Patient Educ Couns. 2002 Dec;48(3):201-6. doi: 10.1016/s0738-3991(02)00171-4. — View Citation

Tam TW, Weisner C, Mertens J. Demographic characteristics, life context, and patterns of substance use among alcohol-dependent treatment clients in a health maintenance organization. Alcohol Clin Exp Res. 2000 Dec;24(12):1803-10. — View Citation

Tsuang MT, Lyons MJ, Eisen SA, Goldberg J, True W, Lin N, Meyer JM, Toomey R, Faraone SV, Eaves L. Genetic influences on DSM-III-R drug abuse and dependence: a study of 3,372 twin pairs. Am J Med Genet. 1996 Sep 20;67(5):473-7. doi: 10.1002/(SICI)1096-8628(19960920)67:53.0.CO;2-L. — View Citation

Umbricht-Schneiter A, Ginn DH, Pabst KM, Bigelow GE. Providing medical care to methadone clinic patients: referral vs on-site care. Am J Public Health. 1994 Feb;84(2):207-10. doi: 10.2105/ajph.84.2.207. — View Citation

Volkow ND. The reality of comorbidity: depression and drug abuse. Biol Psychiatry. 2004 Nov 15;56(10):714-7. doi: 10.1016/j.biopsych.2004.07.007. No abstract available. — View Citation

Von Korff M, Gruman J, Schaefer J, Curry SJ, Wagner EH. Collaborative management of chronic illness. Ann Intern Med. 1997 Dec 15;127(12):1097-102. doi: 10.7326/0003-4819-127-12-199712150-00008. — View Citation

Wagner EH, Austin BT, Von Korff M. Improving outcomes in chronic illness. Manag Care Q. 1996 Spring;4(2):12-25. — View Citation

Weisner C, Matzger H, Tam T, Schmidt L. Who goes to alcohol and drug treatment? Understanding utilization within the context of insurance. J Stud Alcohol. 2002 Nov;63(6):673-82. doi: 10.15288/jsa.2002.63.673. — View Citation

Weisner C, Mertens J, Parthasarathy S, Moore C, Lu Y. Integrating primary medical care with addiction treatment: a randomized controlled trial. JAMA. 2001 Oct 10;286(14):1715-23. doi: 10.1001/jama.286.14.1715. — View Citation

Weisner C, Ray GT, Mertens JR, Satre DD, Moore C. Short-term alcohol and drug treatment outcomes predict long-term outcome. Drug Alcohol Depend. 2003 Sep 10;71(3):281-94. doi: 10.1016/s0376-8716(03)00167-4. — View Citation

Weisner C. The merging of alcohol and drug treatment: a policy review. J Public Health Policy. 1992 Spring;13(1):66-80. — View Citation

Willems S, De Maesschalck S, Deveugele M, Derese A, De Maeseneer J. Socio-economic status of the patient and doctor-patient communication: does it make a difference? Patient Educ Couns. 2005 Feb;56(2):139-46. doi: 10.1016/j.pec.2004.02.011. — View Citation

Zeber JE, Copeland LA, Grazier KL. Serious mental illness, aging, and utilization patterns among veterans. Mil Med. 2006 Jul;171(7):619-26. doi: 10.7205/milmed.171.7.619. — View Citation

Ziedonis DM, Guydish J, Williams J, Steinberg M, Foulds J. Barriers and solutions to addressing tobacco dependence in addiction treatment programs. Alcohol Res Health. 2006;29(3):228-35. — View Citation

* Note: There are 111 references in allClick here to view all references

Outcome

Type Measure Description Time frame Safety issue
Primary patient activation measure Measured by Patient Activation Measure (PAM) from interview data 6 months post baseline
Primary patient engagement in health care (including patient portal use, familiarity and satisfaction with Primary Care physician, and CD treatment length of stay) Measured by data from interviews and Electronic Health Record (EHR) 6 months post baseline
Primary Substance use and mental health outcomes Measures include past 30-day alcohol, drug and total abstinence; Patient Health Questionnaire (PHQ-9) and Addiction Severity Index using interview data 6 months post baseline
Secondary patient activation measure at 12 and 24 months Measured by Patient Activation Measure (PAM) from interview data 12 and 24 months post baseline
Secondary patient engagement in health care at 12 and 24 months Measured by data from interviews and Electronic Health Record (EHR) 12 and 24 months post baseline
Secondary Substance use and mental health outcomes at 12 and 24 months Measures include past 30-day alcohol, drug and total abstinence; Patient Health Questionnaire (PHQ-9) and Addiction Severity Index using interview data 12 and 24 months post baseline
Secondary Health care utilization and cost Measured by data from interviews and adminstrative data 12 and 24 months post baseline
See also
  Status Clinical Trial Phase
Active, not recruiting NCT04070521 - EEG Monitoring in the Emergency Department
Completed NCT00729391 - Women-Focused HIV Prevention in the Western Cape Phase 2/Phase 3
Active, not recruiting NCT03129334 - Preventing Prescription Drug Abuse in Middle School Students N/A
Completed NCT02733003 - Implementation Research for Vulnerable Women in South Africa N/A
Completed NCT02282306 - Phone Interview to Prevent Recurring Opioid Overdoses N/A
Completed NCT02573948 - Feasibility of Interventions on People Who Inject Drugs in Vietnam
Withdrawn NCT01847300 - cSBI-M for Young Military Personnel N/A
Withdrawn NCT01523444 - Advancing Adolescent Screening and Brief Intervention Protocols in Primary Care Settings Phase 3
Completed NCT01481428 - Reducing High Risk Behavior in Treatment Court Phase 1
Completed NCT01591239 - Home-Based Program to Help Parents of Drug Abusing Adolescents N/A
Completed NCT01601743 - Exercise as a Behavioral Treatment for Cocaine Dependence N/A
Active, not recruiting NCT00847548 - Treatment of Intimate Partner Violence and Substance Abuse in a Forensic Setting N/A
Completed NCT01614015 - Building Outcomes With Observation-Based Supervision: An FFT Effectiveness Trial Phase 2
Withdrawn NCT01228890 - Primary Care Internet-Based Depression Prevention for Adolescents (CATCH-IT) Phase 3
Completed NCT01621334 - The Men's Domestic Abuse Check-Up Engages Adult Men Concerned About Their Abusive Behavior and Alcohol or Drug Use Phase 1
Completed NCT00841711 - Transitions: Linkages From Jail To Community N/A
Completed NCT00717444 - Healthy Activities for Prize Incentives N/A
Completed NCT00685074 - Computer-based Brief Intervention for Perinatal Substance Abuse Phase 1/Phase 2
Completed NCT01465490 - Monitoring and Feedback in Substance Abuse Treatment Phase 1/Phase 2
Completed NCT01188434 - Integrating Interventions for Maternal Substance Abuse Phase 1