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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01800890
Other study ID # CP234
Secondary ID
Status Completed
Phase N/A
First received February 22, 2013
Last updated July 14, 2014
Start date February 2013
Est. completion date April 2013

Study information

Verified date July 2014
Source Coloplast A/S
Contact n/a
Is FDA regulated No
Health authority Denmark: Danish Health and Medicines Authority
Study type Interventional

Clinical Trial Summary

The aim of the current clinical investigation is to evaluate the performance and safety of new 2-piece ostomy product concepts.


Description:

The new products have been developed to reduce the degree of leakage and other problems related to ostomy appliances in people with a stoma.


Recruitment information / eligibility

Status Completed
Enrollment 31
Est. completion date April 2013
Est. primary completion date April 2013
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

1. Have given written informed consent and signed letter of authority form.

2. Be at least 18 years of age and have full legal capacity.

3. Be able to handle the appliances themselves

4. Have an ileostomy with a diameter between 15 and 40 mm.

5. Have had their ostomy for at least three months.

6. Use minimum 1 baseplate every third day.

7. Currently use 2-piece flat mechanical coupling product with open bag and a coupling size in the inter val of 43-55mm (both extremes included)

8. Must be able to use custom cut product

9. Accept to test three 2-piece products within the study.

10. Negative result of a pregnancy test for women of childbearing age.

Exclusion Criteria:

1. Use irrigation during the study (flush the stoma with water).

2. Currently receiving or have within the past 2 months received radio- and/or chemotherapy.

3. Currently receiving or have within the past month received local or systemic steroid treatment in the peristomal area.

4. Are pregnant or breastfeeding.

5. Participating in other interventional clinical investigations or have previously participated in this investigation.

6. More than three days wear time as usual change pattern.

7. Currently using ostomy belt

8. Currently using extended wear product (Sensura Xpro, Assura TERA, Dansac NovaLife X3, Hollister Flextend, Convatec Durahesive)

9. Have a loop ileostomy

10. Known hypersensitivity towards any of the test products

11. Suffer from peristomal skin problems that preclude participation in the investigation (assessed by the investigation nurse)

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Supportive Care


Related Conditions & MeSH terms


Intervention

Device:
Coloplast A
Coloplast A is a newly developed 2-piece ostomy appliance
Coloplast B
Coloplast B is a newly developed 2-piece ostomy appliance
Coloplast C
Coloplast C is a newly developed 2-piece ostomy appliance
SenSura Click
The comparator product is the commercial and CE-marked SenSura Click (2-piece) manufactured by Coloplast A/S.

Locations

Country Name City State
Denmark Coloplast A/S Humlebæk

Sponsors (1)

Lead Sponsor Collaborator
Coloplast A/S

Country where clinical trial is conducted

Denmark, 

Outcome

Type Measure Description Time frame Safety issue
Primary Degree of Leakage The degree of leakage is assessed using a 4 point leakage scale developed by Coloplast A/S.
The 4-point leakage scale has four choices
No leakage
Starting to leakage
Leakage
Sudden leakage
Leakage was assessed at every baseplate change
10 days No