| Eligibility |
Inclusion Criteria:
- Provide written informed consent to participate in the study;
- Be 18 years of age or older;
- Agree not to participate in any other oral/dental product studies during the course of
this study;
- Agree to delay any elective dentistry (including dental prophylaxis) until the study
has been completed;
- Agree to use the acclimation toothpaste together with their regular brush and refrain
from any other oral care products (including floss and mouth rinse) between the
Screening and Baseline Visit;
- Agree to use the treatment products and refrain from any form of non-specified oral
hygiene during the treatment periods (after the Baseline Visit), including but not
limited to the use of products such as floss, mouth rinse, or whitening products;
- Agree to return for all scheduled visits and follow study procedures;
- Must have at least 16 natural teeth;
- Be in good general health, as determined by the Investigator/designee based on a
review of the health history/update for participation in the study;
- Agree to refrain from all oral hygiene for at least 12 hours prior to each visit;
- Agree to refrain from eating, chewing gum, drinking and using tobacco for 4 hours
prior to each visit;
- Have 10-20 bleeding sites; and
- Have minimum 6 sampling sites with bleeding and pocket depth =2mm but not deeper than
4mm.
Exclusion Criteria:
- Have had a dental prophylaxis within 2 weeks of plaque sampling visits;
- Have taken antibiotics or used anti-gingivitis / anti-bacterial oral care products
such as chlorhexidine or Listerine within 2 weeks of plaque sampling visits;
- Have rampant caries, open or untreated caries, or advanced periodontitis requiring
prompt treatment;
- Taking allergy medication or any other medication that can affect salivary flow such
as an antihistamine;
- Need an antibiotic prophylaxis prior to dental visits;
- A history of hypersensitivity to oral care products containing hydrogen peroxide or
stannous fluoride;
- A history of hypersensitivity to products containing sodium lauryl sulfate (SLS);
- Are pregnant (Self-reported) or lactating; or
- Have any condition or disease, as determined by the Investigator/Designee based on a
review of the medical history, which could be expected to interfere with examination
procedures or with the subject's safe completion of the study.
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