Striae; Albicantes Clinical Trial
Official title:
Low Level Light Therapy and Fractional Carbon Dioxide Laser in the Treatment of Stria Alba: A Randomised Controlled Study
Stria alba (aka white or atrophic stretch marks) is a very common dermatologic condition that causes major psychological distress to those afflicted. We study the effect of low level light therapy using infra red diode 808/915 nm laser in comparison to fractional CO2 alone and combined both therapies.
All patients will be subjected to the following:
- Written informed consent.
- Detailed history and clinical evaluation.
The treated areas will be photographed (in standardized settings of light and position) and
measured in order to allow comparison and assessment of striae improvement following
treatment.
Patients will be allocated according to randomization into one of 3 arms:
Arm A will be treated by fractional CO2 laser. Arm B will be treated by low level light
therapy (LLLT). Arm C will be treated with a combination of fractional CO2 laser and LLLT.
Digital photographs will be taken for each patient, at the baseline and 1 and 3 months after
last session and the width of the widest striae in each patient will be measured at the same
time. Patients will be assessed before and after treatment by one unblinded and 2 blinded
investigators to measure the clinical improvement on a 4-point scale by comparing the
photographs. The criteria for evaluation using a quartile grading scale will be as follows;
0=no improvement, 1=mild improvement (<25%), 2=moderate improvement (26% - 50%), 3=good
improvement (51% -75%), 4=excellent improvement (>76%).
In addition, a patient satisfaction score will be rated using the following scale; 0=not
satisfied, 1=slightly satisfied, 2= satisfied, 3=very satisfied, 4=extremely satisfied as
well as patients' satisfaction questionnaire (Yang and Lee; 2011).
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT03750422 -
Stretch Marks on Abdomen
|
N/A | |
| Recruiting |
NCT04092881 -
Efficacy of Short Pulsed 1064 nm Nd-YAG Laser Versus 10600 nm Fractional CO2 Laser in Treatment of Striae Alba
|
N/A |