Clinical Trials Logo
  1. Home
  2. Stress Urinary Incontinence
  3. NCT04412876
  4. Details
NCT04412876 Clinical Trial

Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled Study

Stress Urinary Incontinence Clinical Trial

Official title:
Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled Study

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT04412876
Other study ID # 109017-F
Secondary ID
Status Withdrawn
Phase Phase 3
First received
Last updated
Start date May 31, 2020
Est. completion date June 3, 2021

Study information
Verified date June 2021
Source Far Eastern Memorial Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

To assess the impact of Duloxetine and Imipramine on therapeutic efficacy, psychological distress, sexual function, bladder wall structure and blood flow in women

Description:

To assess the impact of Duloxetine and Imipramine on therapeutic efficacy, psychological distress, sexual function, bladder wall structure and blood flow in women

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date June 3, 2021
Est. primary completion date May 31, 2020
Accepts healthy volunteers No
Gender Female
Age group 25 Years and older
Eligibility Inclusion Criteria: - Stress urinary incontinence Exclusion Criteria: 1. Take monoamine oxidase 2. Myocardial infarction critical,cardiovascular insufficiency (such as room blocking, arrhythmia, blood-soaked heart failure, myocardial infarction, stroke and excessive heartbeat). 3. Allergy to duloxetine or imipramine 4. Uncontrolled angular glaucoma patients 5. Pregnant women

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Duloxetine
Duloxetine 30 mg qd
• Imipramine
Imipramine 25mg qd

Locations
Country Name City State
Taiwan Department of Obstetrics and Gynecology, Far-Eastern Memorial Hospital Banqiao New Taipei

Sponsors (1)
Lead Sponsor Collaborator
Far Eastern Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome
Type Measure Description Time frame Safety issue
Other the score of Overactive Bladder Symptom Score Between-group difference in the score of Overactive Bladder Symptom Score 8 weeks
Other the score of King's health questionnaires Between-group difference in the score of King's health questionnaires 8 weeks
Other the score of Brief symptom rating scale Between-group difference in the score of Brief symptom rating scale 8 weeks
Other the score of Female sexual function index Between-group difference in the score of Female sexual function index 8 weeks
Other Blood flow index of the bladder Between-group difference in the changes of blood flow index of the bladder 8 weeks
Other Bladder wall thickness Between-group difference in the changes of Bladder wall thickness 8 weeks
Primary the score of International Consultation on Incontinence Questionnaire-Urinary Incontinence Between-group difference in the score of International Consultation on Incontinence Questionnaire-Urinary Incontinence 8 weeks
Secondary the score of Urgency Severity Scale Between-group difference in the score of Urgency Severity Scale 8 weeks
See also
  Status Clinical Trial Phase
Recruiting NCT04829357 - Post Market Clinical Follow-up Study on TVT ABBREVO® Continence System
Completed NCT05493735 - Lidocaine for Pessary Check Pain Reduction Phase 3
Completed NCT04512053 - A Phase 2 Study of TAS-303 in Female Patients With Stress Urinary Incontinence Phase 2
Active, not recruiting NCT06224335 - Measurement of Intravaginal and Intra-abdominal Pressure and Pad Test During Sports Activities (SPORTVAGPRES)
Recruiting NCT05304312 - The Role of Kegel Exercises Book to Improve Treatment in Stress Urinary Incontinence Women N/A
Not yet recruiting NCT05527665 - Sexual Fonction and Discomfort in Women After Midurethral Sling Surgery, Using PPSSQ
Not yet recruiting NCT04558762 - Ten Years Follow-up After Insertion of a MUS (Mid Urethral Sling) Due to Stress Urinary Incontinence
Withdrawn NCT02524366 - A Study of Transcorporal Versus Standard Artificial Urinary Sphincter Placement N/A
Completed NCT01924728 - Efficacy of Magnetic Stimulation for Stress Urinary Incontinence N/A
Completed NCT01676662 - Solace European Confirmatory Trial N/A
Unknown status NCT01455779 - Lyrette: Renewing Continence Objective and Subjective Efficacy Study N/A
Terminated NCT01029106 - Gynecare TVT Secur for the Management of Stress Urinary Incontinence (SUI) N/A
Completed NCT01770691 - Preliminary Performance Study of the New TIPI Device in the Prevention of Stress Urinary Incontinence N/A
Withdrawn NCT00573703 - Laparoscopic Burch Colposuspension Versus Transobturatory Tape for the Treatment of Female Urinary Stress Incontinence Phase 4
Completed NCT01123096 - Is the Cough Stress Test Equivalent to the 24 Hour Pad Test in the Assessment of Stress Incontinence? N/A
Completed NCT00234754 - Trans-Obturator Tape Versus Trans-Vaginal Tape for Stress Urinary Incontinence in Women N/A
Completed NCT00441454 - Retropubic vs. Transobturator Tension-free Vaginal Tape N/A
Completed NCT03985345 - Prospective Evaluation of the Connected EMY Biofeedback Probe in the Management of Stress Urinary Incontinence. N/A
Active, not recruiting NCT03671694 - Laser Vaginal Treatment for SUI N/A
Completed NCT04097288 - Effects of Single Dose Citalopram and Reboxetine on Urethral and Anal Closure Function on Healthy Female Subjects Phase 1