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Host Response to Pessaries in Microbial Communities of the Postmenopausal Vagina

Stress Urinary Incontinence Clinical Trial

Official title:
Host Response to Pessaries in Microbial Communities of the Postmenopausal

Clinical Trial Summary

The ability to determine the postmenopausal vaginal environment and the impact of pessary use could help to maximize pessary therapy and non-surgical treatment for such a prevalent problem.

Clinical Trial Description

The study will advance the care of elderly patients through providing data to maximize non-surgical options to those at high risk for having surgery and its attending morbidity. In characterizing substantive differences in the vaginal environment of successful and unsuccessful pessary users, the investigators can identify elderly patients at higher risk of adverse events with pessary use as well as novel targets for the pharmacologic treatment of the altered vaginal microbiota and endogenous AMP levels, potentially allowing patients to continue with non-surgical therapies rather than pursuing surgical intervention. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02605135
Study type Observational
Source Loyola University
Contact
Status Completed
Phase
Start date April 2016
Completion date June 2018
View Details
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