Necrotizing Bacterial Dermohypodermitis-necrotizing Fasciitis Mono- or Multi-microbial Streptococcus Beta-haemolytic — STREPTO-FAST  

Streptococcus Infection Clinical Trial

Official title: Necrotizing Bacterial Dermohypodermitis-necrotizing Fasciitis (DHBN-FN) Mono- or Multi-microbial Streptococcus Beta-haemolytic: Study of Carriage in Patients and Their Entourage

Status Not yet recruiting

Clinical Trial Summary

The aim of the study is to evaluate streptococcal carriage by swab, pharyngeal, anal and perineal in patients with DHBN-FN, in the entourage living under the same roof as well as patients with erysipelas

The main hypothesis is the major role of chronic porting of patients and entourage in DHBN-FN to SBH.

Indeed, the chronic pharyngeal / anal / perineal carriage could be a gateway following a transient bacteremia for a DHBN-FN.

The transmission of germs from the surrounding to the patient plays a major role:

At the gateway level in the case of exogenous DHBN-FN At the origin of chronic carriage in the case of endogenous DHBN-FN Transmission of germs from the patient to the surrounding area also plays an important role in increasing the risk of invasive SBH infections in the surrounding area.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Fasciitis
• Fasciitis, Necrotizing
• Streptococcal Infections
• Streptococcus Infection

• NCT number: NCT03976024
• Study type: Interventional
• Source: Assistance Publique - Hôpitaux de Paris
• Contact: Olivier CHOSIDOW, Professor
• Phone: +33(1)49812500
• Email: olivier.chosidow@aphp.fr
• Status: Not yet recruiting
• Phase: N/A
• Start date: September 1, 2020
• Completion date: November 1, 2020