Assessing the Functional & Psychosocial Impact of Strabismus in Asian

Status Completed

Clinical Trial Summary

Studies suggest that strabismus has a negative impact on a person's self-image, interpersonal relationships, emotional and psychosocial state (4-15). There are, however, few such studies based in Asia, and the functional and psycho-social impact of disease is often neglected in our management of strabismus in Singapore. The aim of this pilot study is to measure quality-of-life (QOL) among strabismic children in Singapore so as to better understand the functional and psychosocial issues faced by these children in their daily living. The investigators also hope to evaluate the performance of the Intermittent Exotropia Questionnaire (IXTQ) (2) and Adult Strabismus Quality of Life Questionnaire (AS-20) (1) and to determine if differences between child and parental perceptions exist.

60 children with strabismus presenting to the KKWCH Eye Centre and their parents will be invited to participate in the study and answer questions in 2 Pediatric Eye Disease Investigator Group (PEDIG)-validated questionnaires (i.e. the IXTQ and AS-20). 30 children aged 5-7 years will answer the 12-question IXTQ (5-7 years), while 30 children aged 8-16 years will answer the 12-question IXTQ (8-16 years) and the 20-question AS-20 questionnaires. Their parents will answer the self-administered IXTQ child-proxy (12 questions), IXTQ parental (17 questions) and modified AS20 child-proxy questionnaires (20 questions). For comparison, 60 aged-matched children without strabismus or amblyopia (30 aged 5-7 years, and 30 aged 8-16) and their parents will also be invited to answer similar questionnaires (controls).

Results will be analysed question-by-question and then by composite score, and comparison will be made between child and parental-proxy measures, as well as with scores obtained from myopic children. It is hoped, that from this study, we will be able to assess the usefulness of the IXTQ and AS-20 instruments as measures of QOL in strabismic children, and to assess the feasibility of its use in a larger study looking at the impact of strabismus and its treatment in Singaporean children.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Strabismus

Clinical Trial Details

NCT number	NCT01608828
Study type	Observational
Source	Singapore National Eye Centre
Contact
Status	Completed
Phase	N/A
Start date	May 2012
Completion date	May 2014

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03596138` - Reliability and Reproducibility of Automated Angular Measurement in Strabismus
Completed	`NCT04432181` - Comparison of Deviation Types Among Astigmatic Children With Or Without Amblyopia
Recruiting	`NCT03713268` - Intraoperative OCT Guidance of Intraocular Surgery II
Recruiting	`NCT04770519` - Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
Completed	`NCT01512355` - The Effect of Dexmedetomidine on Decreasing Emergence Agitation and Delirium in Pediatric Patients Undergoing Strabismus Surgery	N/A
Completed	`NCT00461656` - Povidone-iodine Antisepsis for Strabismus Surgery	Phase 4
Completed	`NCT00535938` - MDs on Botox Utility (MOBILITY)	N/A
Completed	`NCT01109459` - Multimodal Physician Intervention to Detect Amblyopia	N/A
Not yet recruiting	`NCT06035757` - The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery	Phase 4
Completed	`NCT01430247` - Vision Screening for the Detection of Amblyopia	N/A
Recruiting	`NCT04416776` - Validation of the Utility of Strabismus Intelligent Diagnostic System
Recruiting	`NCT04353960` - The Alaska Oculocardiac Reflex Study
Terminated	`NCT02246556` - Dichoptic Virtual Reality Therapy for Amblyopia in Adults	Phase 1
Completed	`NCT01726842` - Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner	N/A
Completed	`NCT00001143` - Development of the Eye Motor System During the First 7 Months of Life in Infants With and Without a Family History of Cross-Eye	N/A
Completed	`NCT04303832` - Exercise Interventions of Eye Muscles Post Strabismus Surgery	N/A
Completed	`NCT03806270` - Hydroxyzine Dihydrochloride Premedication is a Necessity for Strabismus Surgery
Recruiting	`NCT05425589` - Adjustable Strabismus Surgery	N/A
Completed	`NCT00559234` - Potential Research Participants for Future Studies of Inherited Eye Diseases	N/A
Completed	`NCT02570555` - Strabismus Surgery and Driving Ability

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Assessing the Functional and Psychosocial Impact of Strabismus in Asian Children Using the AS-20 and IXTQ Questionnaires

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms