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Strabismus clinical trials

View clinical trials related to Strabismus.

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NCT ID: NCT04549844 Recruiting - Strabismus Clinical Trials

Peribulbar Block for Prevention of Oculocardiac Reflex

Start date: August 14, 2019
Phase: Phase 4
Study type: Interventional

Strabismus is a common ophthalmic problem in Egypt that usually requires surgical correction. This surgery primarily aims to improve alignment of visual axis but may be required only for cosmetic reasons. General anesthesia is mandatory for most cases however a concomitant local anesthetics administration is preferable to improve patient satisfaction, decrease postoperative analgesic requirements and reduce post-operative pain. Oculocardiac reflex is a noted serious complication that accompanies such surgeries and may be life threatening. Oculocardiac reflex (OCR) is one of the main challenges that face anesthesiologists during strabismus surgery. The incidence of OCR varies from 16 to 82 % in strabismus surgeries and this wide range does depend on the anesthetic agents, premedications, and the definition of OCR being used. Maintenance of adequate depth of anesthesia and the use of anti-cholinergic is the mainstay to reduce this risk. OCR is usually defined as a decrease in heart rate of more than 20 % from the baseline. This reflex is triggered by the pressure on the extra ocular muscles (EOM) or eyeball, orbital hematoma or trauma, the afferent limb is from orbital contents to ciliary ganglion then to the sensory nucleus of the trigeminal nerve near the fourth ventricle through the ophthalmic division of the trigeminal nerve. The main response of this reflex is transmitted through the vagus to the heart. This vagal stimulation leads to a decrease in heart rate (sinus bradycardia), contractility and arrhythmias such as atrioventricular block, ventricular fibrillation up to cardiac arrest. The incidence of the OCR decreases with age and tends to be more pronounced in young healthy patients. It has been suggested that the anesthetic agents used during surgery influence the incidence of OCR. To date, the only successful method to interrupt an OCR is to stop the EOM traction, and then proceed with caution as surgery continues. Depth of anesthesia is another presumed factor having an impact on reducing of OCR incidence. The response to surgical stimulus can be minimized or stopped with the help of peribulbar block.

NCT ID: NCT04485273 Completed - Emergence Agitation Clinical Trials

Effect of Dexmedetomedine in Subtenon's Block on Emergence Agitation in Pediatric Strabismus Surgery

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

The study is conducted to evaluate the effects of dexmedetomedine in subtenon's block in conjunction to general anesthesia under sevoflurane anesthesia on emergence agitation, intraoperative hemodynamic stability, postoperative pain, nausea and vomiting in patients undergoing strabismus surgery.

NCT ID: NCT04485117 Completed - Strabismus Clinical Trials

Propofol Versus Sevoflurane Anesthesia in Pediatric Strabismus Surgery: Feasibility of BIS Monitoring

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

This study is conducted to evaluate importance of bispectral index (BIS) monitoring in patients undergoing strabismus surgery when using propofol in comparison to sevoflurane anesthesia regarding their effects on oculocardiac reflex, intraoperative hemodynamic stability, emergence agitation, postoperative pain, nausea and vomiting.

NCT ID: NCT04432181 Completed - Amblyopia Clinical Trials

Comparison of Deviation Types Among Astigmatic Children With Or Without Amblyopia

Start date: September 4, 2018
Phase:
Study type: Observational [Patient Registry]

the records of astigmatic children were reviewed and any deviation was investigated at near and distance. refractive errors, stereopsis, convergence insufficiency were also evaluated. children were divided into two groups according to the presence of amblyopia and ocular deviations and other parameters were compared between groups.

NCT ID: NCT04416776 Recruiting - Strabismus Clinical Trials

Validation of the Utility of Strabismus Intelligent Diagnostic System

Start date: September 1, 2019
Phase:
Study type: Observational

Strabismus affects approximately 0.8%-6.8% of the world's population and appears by the age of 3 years in 65% of affected individuals. Manual measurement of deviation is often laborious and highly dependent on the experience of the specialist and the cooperation of the patients. Current strabismus evaluation technologies are heavily dependent on model eyes. Here, the investigators use deep learning to develop an artificial intelligence (AI) platform consisting of three deep learning (DL) systems to screen strabismus, evaluate deviation and propose a surgical plan based on corneal light-reflection photos. The investigator also conduct clinical trial to validate its versatility in clinical practice.

NCT ID: NCT04353960 Recruiting - Bradycardia Clinical Trials

The Alaska Oculocardiac Reflex Study

AK-OCR
Start date: September 1, 1992
Phase:
Study type: Observational

Observation study monitoring vital signs and anesthetic variables particularly heart rate during prospective, ocular manipulation and specifically uniform tension on extra ocular muscles during strabismus surgery. *IRB approval from 1992 covered in letter from then IRB chair Dr. Judith Whitcomb, Anchorage, Alaska (letter 10/2020).*

NCT ID: NCT04315649 Completed - Amblyopia Clinical Trials

Effect of 3D Movie Viewing on Stereopsis in Strabismus and / or Anisometropic Amblyops

Start date: September 16, 2021
Phase: N/A
Study type: Interventional

This study evaluates the effect of 3D movie viewing on stereopsis recovery in anisometropic and / or strabismus amblyopia and the satisfaction with the intervention.

NCT ID: NCT04310241 Recruiting - Amblyopia Clinical Trials

Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy

Start date: February 21, 2020
Phase:
Study type: Observational

Amblyopia and strabismus are characterized by a reduction in visual acuity, contrast sensitivity, grating acuity, vernier acuity, reading difficulties and binocular visual function deficits. Treated patients have residual visual function deficits. The purpose of the current study is to quantify various visual functions in amblyopic and strabismic participants at baseline, during and at the completion of treatment.

NCT ID: NCT04303832 Completed - Amblyopia Clinical Trials

Exercise Interventions of Eye Muscles Post Strabismus Surgery

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

It will be hypothesized that: - Eye exercises have a positive effect on correction of remaining ocular deviation post strabismus surgery. - Eye exercises have a positive effect on improving amplyobia.

NCT ID: NCT04286945 Completed - Clinical trials for Surgical Procedure, Unspecified

Lateral Rectus Muscle Tendon Elongation

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

To evaluate a technique using resected medial rectus muscle transplantation for elongation of Lateral rectus tendon as a monocular surgery for large angle sensory exotropia.