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The Conversion Therapy of Chemotherapy Plus Camrelizumab in Metastatic Gastric Cancer

Stomach Neoplasms Clinical Trial

Official title:
PD-1 Inhibitor Plus Chemotherapy as Conversion Therapy in Unresectable Gastric Cancer (STARS-GC01): A Single-arm, Single-center, Prospective Clinical Study.

Clinical Trial Summary

Gastric cancer is one of the most common malignant tumors of the digestive tract. Gastric cancer patients diagnosed for the first time in China have a higher proportion of advanced stages and a higher postoperative metastasis rate.Studies have shown that patients with good pathological response after preoperative neoadjuvant therapy (such as tumor regression grade, TRG0 or 1) have a better prognosis.The purpose of this study is to treat patients with advanced gastric cancer who are difficult to perform R0 surgery with chemotherapy combined with immunotherapy. At the same time as the primary cancerous lesions are reduced, the distant metastatic lesions are effectively controlled in order to perform R0 surgery and to improve the survival rate of patients with advanced gastric cancer.

Clinical Trial Description

The interventions include camrelizumab and chemotherapy selected based on the use of different metastatic sites as conversion therapy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04694183
Study type Interventional
Source The First Hospital of Jilin University
Contact
Status Completed
Phase Phase 2
Start date August 17, 2020
Completion date May 6, 2023
View Details
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