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Study of Vismodegib in Advanced Gastric Adenocarcinoma Patients With SMO Overexpression

Stomach Neoplasms Clinical Trial

Official title:
Phase II, Single-arm Study of Vismodegib in Advanced Gastric Adenocarcinoma Patients With SMO Overexpression

Clinical Trial Summary

There is no accepted standard therapy for patients with advanced gastric cancer who have progressed during or after second-line therapy. The role of 3rd line treatment in advanced gastric cancer has not been proven. As a novel target of gastric cancer, SMO overexpression is chosen in this study, and the investigators plan this study to evaluate the efficacy and safety of vismodegib in gastric cancer. The doses of vismodegib are based on trials of basal cell carcinoma.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03052478
Study type Interventional
Source Samsung Medical Center
Contact
Status Completed
Phase Phase 2
Start date February 10, 2017
Completion date September 10, 2020
View Details
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