Stomach Neoplasm Clinical Trial
Official title:
Ultra Structure of Peritoneum at Electronic Microscopy in Control Subjects and Patients With Gastric Cancer
Verified date | July 2009 |
Source | University of Chile |
Contact | n/a |
Is FDA regulated | No |
Health authority | Chile: Instituto de Salud Pública de Chile |
Study type | Observational |
Peritoneal metastases appear in a great proportion of patients affected by gastric carcinoma. Involved mechanisms are poorly understood though experimentally it has been demonstrated that neoplastic cells exfoliated from primary tumor can only implant and proliferate in areas of damaged peritoneum. Objectives: to study ultra-structure of peritoneal surface by electronic microscopy in control subjects and in patients with early or locally advanced gastric cancer looking for spontaneous changes in peritoneal surface not related with surgical injury.
Status | Completed |
Enrollment | 18 |
Est. completion date | December 2004 |
Est. primary completion date | July 2004 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - patients with operable local gastric adenocarcinoma Exclusion Criteria: - previous abdominal surgery - previous open or blunt abdominal trauma - history of inflammatory bowel disease or Typhoid Fever, Gallstone disease, chemotherapy or radiotherapy, or any other abdominal condition that could alter peritoneal integrity. - All other gastric malignancies such as lymphomas, GIST, carcinoids |
Observational Model: Case Control, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Chile | Department of Surgery, Clinical Hospital, University of Chile | Santiago | Region Metropolitana |
Lead Sponsor | Collaborator |
---|---|
University of Chile |
Chile,
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