Clinical Trials Logo
  1. Home
  2. Stevens-Johnson Syndrome
  3. NCT02037347

Study to Evaluate the Use of Palifermin to Treat Toxic Epidermal Necrolysis

Stevens-Johnson Syndrome Clinical Trial

Official title:
Palifermin Treatment of Toxic Epidermal Necrolysis

Clinical Trial Summary

To test the ability of palifermin (a recombinant human keratinocyte growth factor) to decrease mucocutaneous injury and to promote epithelial repair in Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis Overlap, diseases in which there is extensive sloughing of the skin and mucosa, including that of the eyes, gastrointestinal tract, respiratory and genitourinary systems.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02037347
Study type Interventional
Source Yale University
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date October 2010
Completion date December 2014
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT03659227 - Drug Reactions Sampling (COLLECTIONTOXIDERMIES)
Completed NCT01696500 - Phase III Clinical Trial of NPB-01 in Patients With Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis Unresponsive to Corticosteroids. Phase 3
Withdrawn NCT02126020 - Topical Infliximab in Autoimmune Eyes With Keratoprosthesis Phase 1/Phase 2
Active, not recruiting NCT05520086 - Clinical Trial to Evaluate Safety and Efficacy of Cell Therapy in Patients With Cicatricial Conjuntivitis. Phase 1/Phase 2
Completed NCT06263140 - Vitamin D Levels in Non-immediate Drug Hypersensitivity Case-control Study
Available NCT02149732 - Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation Phase 1/Phase 2
Recruiting NCT05284929 - Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population
Recruiting NCT02987257 - NATIENS: Optimal Management and Mechanisms of SJS/TEN Phase 3
Completed NCT02945176 - Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis Implantation N/A
Not yet recruiting NCT03585946 - Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis
Recruiting NCT04313725 - Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease N/A
Recruiting NCT03046914 - HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction N/A
Completed NCT01488396 - Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye Phase 4
Withdrawn NCT01256489 - Infliximab to Improve Retention of the Boston Keratoprosthesis in Patients After Stevens Johnson Syndrome/ Toxic Epidermal Necrolysis (SJS/TENS) Phase 1/Phase 2
Active, not recruiting NCT01122303 - Corneal Epitheliotropic Factors in Autologous Serum Eye Drops in Nonautoimmune and Stevens-Johnson Syndrome With Dry Eye N/A
Recruiting NCT05145959 - Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis N/A
Completed NCT00844038 - Stevens-Johnson Syndrome Antimicrobial N/A