Glasgow Natural History Study Of Covered Coronary Interventions — GNOCCI  

Stent Thrombosis Clinical Trial

Official title: Glasgow Natural History Study Of Covered Coronary Interventions

Status Completed

Clinical Trial Summary

Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown. The GNOCCI study aims to evaluate long term outcomes after coronary perforation including patients treated with covered stents.

Clinical Trial Description

Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown. Using an electronic data base, details of all coronary perforations are identified and anonymised patient and procedural details are recorded.Procedural major adverse cardiac events (pMACE) are defined as a composite of death, myocardial infarction, stroke, target vessel revascularization or cardiac surgery within 24 hours of the index procedure. Two independent cardiologists adjudicate outcomes and differences in opinion are resolved by consensus with a third cardiologist.

The overall GNOCCI study aims are:

1. Evaluate procedural and long term outcomes after coronary perforation

2. Long term safety and clinical events in patients treated with covered stents. ;

Related Conditions & MeSH terms

• Coronary Artery Perforation
• Coronary Stent Occlusion
• Stent Thrombosis
• Thrombosis

• NCT number: NCT03862352
• Study type: Observational [Patient Registry]
• Source: NHS National Waiting Times Centre Board
• Status: Completed
• Start date: January 1, 2000
• Completion date: January 1, 2022