Stem Cells Clinical Trial
Official title:
Isolation and Characterization of Mammary Stem Cells
| Verified date | March 23, 2011 |
| Source | National Institutes of Health Clinical Center (CC) |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
Background:
- Cancer stem cells in breast cancer have been identified as a small population of tumor
cells whose self-renewal mechanism is highly deregulated. This deregulation seems to be
necessary for cancer to develop.
- These cells can be identified by certain surface markers that overlap with markers
associated with normal embryonic stem cells.
Objective: To isolate tumor stem cells using the same methods generally used to isolate human
embryonic stem cells.
Eligibility:
- Tissue samples will be obtained from the human cooperative network.
- Samples will include normal tissues from individuals who have no opportunistic diseases
and from individuals with cancer.
Design: Breast cancer stem cells will be isolated, grown in the laboratory and characterized.
| Status | Completed |
| Enrollment | 400 |
| Est. completion date | March 23, 2011 |
| Est. primary completion date | |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | N/A and older |
| Eligibility |
- INCLUSION CRITERIA: The tissue samples will come from the human cooperative network. They have their own set of criteria. We are requesting tissue samples from individuals that are normal as well as those who have cancer. EXCLUSION CRITERIA: The tissue samples will come from the human cooperative tissue network and we are asking for normal samples from individuals who don't have any opportunistic diseases. |
| Country | Name | City | State |
|---|---|---|---|
| United States | National Cancer Institute (NCI), 9000 Rockville Pike | Bethesda | Maryland |
| Lead Sponsor | Collaborator |
|---|---|
| National Cancer Institute (NCI) | National Institutes of Health (NIH) |
United States,
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