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Clinical Trial Summary

The investigators hope to find the proof of principle concept from this pilot study so that the investigators can design a clinical trial based on the results of the explanatory hypothesis.


Clinical Trial Description

Hematopoietic Stem Cell Transplant (HSCT) survivors are at an increased risk for premature aging. No one has evaluated the biologic markers of premature aging and senescence in HSCT survivors and their correlation with clinical outcomes, lifestyle, and nutrition. The investigators will evaluate age-related changes in HSCT survivors, with specified measures of premature aging, and employ therapeutic opportunities based on targeting senescent cells by conducting the first in-human pilot study of senolytic drugs (in HSCT survivors utilizing a combination of senolytics). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02652052
Study type Interventional
Source Mayo Clinic
Contact
Status Recruiting
Phase N/A
Start date March 1, 2016
Completion date October 15, 2024

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