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Stem Cell clinical trials

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NCT ID: NCT06004063 Recruiting - Stem Cell Clinical Trials

Safety, Tolerability, and Efficacy of Enteral Nutrition Versus Paranteral Nutrition in Hematopoietic Stem Cell Transplant Patients: A Pilot Randomized Controlled Study

Start date: August 4, 2023
Phase: N/A
Study type: Interventional

The goal of this research study is to learn if feeding someone after a stem cell transplant is safe and practical.

NCT ID: NCT05939817 Completed - Keloid Clinical Trials

The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trial

Start date: October 1, 2021
Phase: Phase 4
Study type: Interventional

The objective of this study is to observe the potency of umbilical cord-derived mesenchymal stem cells (UC-MSC) and umbilical cord-derived conditioned medium (UC-CM), or triamcinolone acetonide (TA) in keloid therapy, measured by the decrease in the type 1:3 collagen ratio and the increase of IL-10 levels carried out using CONSORT statement.

NCT ID: NCT05887804 Completed - Keloid Clinical Trials

Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide Injection as Keloid Therapy: A Randomised Controlled Trial

Start date: October 1, 2021
Phase: Phase 4
Study type: Interventional

This study is a double-blind randomized controlled trial (RCT) examining the effect of intralesional injection of umbilical cord-derived mesenchymal stem cells (UC-MSC), umbilical cord-derived conditioned medium (UC-CM), or triamcinolone acetonide (TA) on keloids carried out using CONSORT statement. Research is directed at studying keloid volume reduction and changes in POSAS score.

NCT ID: NCT04641533 Completed - Periodontal Pocket Clinical Trials

Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction

Start date: January 20, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the clinical and radiographic effectiveness of Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF combined with dental pulp stem cell (DPSC) application to the extraction socket of mandibular third molars.

NCT ID: NCT04313894 Recruiting - Gonarthrosis Clinical Trials

WHARTON JELLY ORIGINATED MESENCHIAL STEM CELL in GONARTHROSIS

WHAMKO
Start date: January 1, 2019
Phase: Phase 2
Study type: Interventional

Osteoarthritis (OA) is a progressive disease characterized by degeneration of the joint cartilage, which is involved in the immune system leading to proinflammatory cytokine and metalloproteinase release. Knee osteoarthritis is the most common form. The healing is very slow and the damage is not fully recovered, so the degeneration process continues and no treatment modalities completely remove this process. Various methods are used in the treatment of OA and total joint replacement is performed in the patients with OA recently. Ten patients with Kellgren-Lawrence grade II-III knee OA who had been applied for knee pain and received conservative treatment for 6 months and had no benefit will be taken to study. Patients will be assessed 7 (V1-7) times during the study. Clinical, immunologic and radiological treatment effectiveness and clinical improvement will be evaluated at the beginning of the treatment and in all follow-up patients participating in the study.

NCT ID: NCT03947450 Recruiting - Amputation Clinical Trials

Autologous Volar Fibroblast Injection Into the Stump Site of Amputees

Start date: September 5, 2019
Phase: Phase 2
Study type: Interventional

This study is a clinical trial testing the safety and efficacy of volar fibroblast (skin cells from the palm or sole) injections for thickening the epidermal (skin) layer at the stump site in people with below the knee amputations. The study will enroll adults seen at Johns Hopkins.