Compare Train and 3D-4D Left Ventricular Systolic Function in Subjects Suffering From Dystrophy and Healthy Subjects

Steinert's Disease Clinical Trial

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02930408
• Other study ID #: STEINECHO
• Status: Terminated
• Phase: N/A
• First received: October 10, 2016
• Last updated: October 11, 2016
• Start date: January 2014

Study information

• Verified date: August 2016
• Source: Poitiers University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Agence Nationale de Sécurité du Médicament et des produits de santé
• Study type: Interventional

Clinical Trial Summary

Steinert's disease is an orphan disease. The prognosis of patients with this disease is conditioned by cardiac involvement. Search an early stage alterations in contractile function in subjects suffering from dystrophy would detect patients at risk of sudden death. The first stage of work is to validate the tools to detect early stage of infringement systolic function in a population of patients with myotonic dystrophy.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 70
• Est. primary completion date: July 2015
• Gender: Both
• Age group: 18 Years to 99 Years

Eligibility

Inclusion Criteria:

• patients suffering from muscular dystrophy type 1 followed CHU Poitiers.

• age = 18 years

Exclusion Criteria:

• duration QRS> 120 ms ECG permanent ventricular stimulation

• trouble segmental kinetic obvious to echocardiography in visual analysis

Study Design

N/A

Related Conditions & MeSH terms

• Myotonic Dystrophy
• Steinert's Disease

Intervention

Procedure:
• electrocardiogram

• Echocardiography

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Poitiers University Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Ventricular Ejection Fraction Left 3D		Immediately
Primary	Global longitudinal systolic Strain		Immediately
Primary	Strain of the dispersion index		Immediately