Study of Oral Papillomavirus In Teens and Twenties

STD Clinical Trial

— SPITT  

Official title:

Short-term Natural History of Oral HPV Infection Among Young Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00994019
• Other study ID #: 2422
• Status: Completed
• Start date: January 2010
• Est. completion date: October 2014

Study information

• Verified date: January 2020
• Source: Johns Hopkins Bloomberg School of Public Health
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Recently human papillomavirus (HPV) has been recognized to cause some oropharyngeal (tonsil) cancer. But very little is known about oral HPV infection and risk factors. This study will evaluate how common oral HPV infection is, what sexual behaviors are associated with risk for infection, and how long infections tend to last.

Description:

18-25 year old individuals are being recruited from STD clinics in Baltimore County and followed every three months for this study.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 550
• Est. completion date: October 2014
• Est. primary completion date: October 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 26 Years

Eligibility

Inclusion Criteria:

• Age 18 -26 years

Exclusion Criteria:

• Never received HPV vaccine (Gardasil or Cervarix)

Related Conditions & MeSH terms

• STD

Locations

Country	Name	City	State
United States	Baltimore County Eastern Health Center	Baltimore	Maryland
United States	Baltimore County Woodlawn Health Centers	Baltimore	Maryland

Sponsors (1)

Lead Sponsor	Collaborator
Johns Hopkins Bloomberg School of Public Health

Country where clinical trial is conducted

United States, 

References & Publications (2)

D'Souza G, Kluz N, Wentz A, Youngfellow RM, Griffioen A, Stammer E, Guo Y, Xiao W, Gillison ML. Oral Human Papillomavirus (HPV) Infection among Unvaccinated High-Risk Young Adults. Cancers (Basel). 2014 Aug 14;6(3):1691-704. doi: 10.3390/cancers6031691. — View Citation

D'Souza G, Wentz A, Kluz N, Zhang Y, Sugar E, Youngfellow RM, Guo Y, Xiao W, Gillison ML. Sex Differences in Risk Factors and Natural History of Oral Human Papillomavirus Infection. J Infect Dis. 2016 Jun 15;213(12):1893-6. doi: 10.1093/infdis/jiw063. Epu — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Oral HPV infection	Oral rinse samples collected prospectively for 24 months	24 months