Weight Loss Clinical Trial
Official title:
Using Resistance Exercise and Protein Consumption to Protect Bone Health During Weight Loss
The purpose of this study is to determine if post-exercise protein supplementation can rescue the anabolic response of muscle and bone to resistance exercise during caloric restriction.
1. Preliminary Testing Prior to the study start, participants will be weighed and body
composition will be determined using bioimpedance analysis. Then participants will
undergo a 5RM barbell back squat exercise testing procedure.
2. Randomization
Participants will proceed through each of the following conditions lasting 3 days:
CON: Participants will be in energy balance and consume 1.2 g protein/kg BW/day.
Participants will be provided 30 g maltodextrin post-exercise.
CR+C: Participants will be restricted to 15 kcal/kg FFM/day and consume 1.2 g protein/kg
BW/day. Participants will be provided 30 g maltodextrin post-exercise.
CR+P: Participants will be restricted to 15 kcal/kg FFM/day and consume 1.2 g protein/kg
BW/day. Participants will be provided 30 g whey protein post-exercise.
3. Diet Prescription Dietary energy intake will be controlled using clinical products,
maltodextrin and whey protein isolate to meet target energy intakes. Participants will
receive calcium and Vitamin D supplementation throughout the study.
4. Exercise Prescription Participants will perform one bout of 5 sets of 5 repetitions of
barbell back squat exercise on the morning of Day 3 each condition. Additional exercise
and intense physical activity will be prohibited.
5. Assessments Body weight and composition (DXA + BIA), fasting blood draws for assessment
of metabolic and anabolic hormones and questionnaires will be conducted before and after
each condition. A 24-hour serial blood draw procedure will be conducted following each
workout session on each Day 3.
6. Washout Once a participant completes a study condition, participants will continue to
take daily body weights at home for up to one week. Then participants will be required
to wait one more week before completing their next condition during which they will
resume regular diet and physical activity.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04506996 -
Monday-Focused Tailored Rapid Interactive Mobile Messaging for Weight Management 2
|
N/A | |
Active, not recruiting |
NCT04420936 -
Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care for Our Program
|
N/A | |
Terminated |
NCT03316105 -
Effect of T6 Dermatome Electrical Stimulation on Gastroduodenal Motility in Healthy Volunteers
|
N/A | |
Completed |
NCT03700736 -
The Healthy Moms Study: Comparison of a Post-Partum Weight Loss Intervention Delivered Via Facebook or In-Person Groups
|
N/A | |
Active, not recruiting |
NCT04353726 -
Knowledge-based Dietary Weight Management.
|
N/A | |
Completed |
NCT02948283 -
Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia
|
Phase 1 | |
Completed |
NCT03377244 -
Healthy Body Healthy Souls in the Marshallese Population
|
N/A | |
Completed |
NCT02877004 -
LLLT for Reducing Waste Circumference and Weight
|
N/A | |
Active, not recruiting |
NCT04327141 -
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
|
N/A | |
Completed |
NCT03929198 -
Translation of Pritikin Program to the Community
|
N/A | |
Recruiting |
NCT05249465 -
Spark: Finding the Optimal Tracking Strategy for Weight Loss in a Digital Health Intervention
|
N/A | |
Recruiting |
NCT05942326 -
Sleep Goal-focused Online Access to Lifestyle Support
|
N/A | |
Completed |
NCT00535600 -
Effects of Bariatric Surgery on Insulin
|
||
Not yet recruiting |
NCT03601273 -
Bariatric Embolization Trial for the Obese Nonsurgical
|
Phase 1 | |
Active, not recruiting |
NCT04357119 -
Common Limb Length in One-anastomosis Gastric Bypass
|
N/A | |
Completed |
NCT03139760 -
POWERSforID: A Telehealth Weight Management System for Adults With Intellectual Disability
|
N/A | |
Completed |
NCT02948517 -
Time Restricted Feeding for Weight Loss and Cardio-protection
|
N/A | |
Completed |
NCT02945410 -
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
|
N/A | |
Completed |
NCT03210207 -
Gastric Plication in Mexican Patients
|
N/A | |
Recruiting |
NCT02559479 -
A Study to Assess the Effect of a Normal vs. High Protein Diets in Carbohydrates Metabolism in Obese Subjects With Diabetes or Prediabetes
|
N/A |